Tan Lab | DSigDB

Gene Set: D4 : Boss - astrazeneca brand of bumetanide

Collection

D4 : Boss

Chemical Name

astrazeneca brand of bumetanide ( From PubChem : BUMETANIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
364.416 g/mol	3	7	4.8906	True

Structure

InChI

InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)

InChIKey

Links

Gene (17 / 23)

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Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			ABCC10
BOSS	Text Mining			AQP4
BOSS	Text Mining			CA3
BOSS	Text Mining			INS
BOSS	Text Mining			NONO
BOSS	Text Mining			NPPB
BOSS	Text Mining			SLC12A1
BOSS	Text Mining			SLC12A2
BOSS	Text Mining			SLC12A4
BOSS	Text Mining			SLC12A5
BOSS	Text Mining			SLC6A3
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		MAP4K2	-	GI(Protien) :
PubChem	Potency	uM	5.805	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	6.513	NFE2L2	-	GI(Protien) :
PubChem	None	uM		SLC12A5	-	GI(Protien) :
PubChem	None	uM		SLC12A5	-	GI(Protien) :
ChEMBL	Potency	nM	15848.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	25118.900	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	5804.800	NFE2L2	-	Target : CHEMBL1075094

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