Tan Lab | DSigDB

Gene Set: D4 : Boss - aromasil

Collection

D4 : Boss

Chemical Name

aromasil ( From PubChem : EXEMESTANE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
296.403 g/mol	0	2	4.0295	True

Structure

InChI

InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1

InChIKey

BFYIZQONLCFLEV-DAELLWKTSA-N

Links

Gene (15 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			CYP2C8
BOSS	Text Mining			EGF
BOSS	Text Mining			EGFR
BOSS	Text Mining			ERBB2
BOSS	Text Mining			ERBB2
BOSS	Text Mining			EREG
BOSS	Text Mining			ESR1
BOSS	Text Mining			IGFBP1
BOSS	Text Mining			MTOR
BOSS	Text Mining			NR4A1
BOSS	Text Mining			PGR
BOSS	Text Mining			SGSM3
PubChem	Potency-Replicate_1	uM	0.030	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.601	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.042	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.413	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	2.033	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.660	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	8.414	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :

Download gene sets

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