Tan Lab | DSigDB

Gene Set: D4 : Boss - aminazin

Collection

D4 : Boss

Chemical Name

aminazin ( From PubChem : CHLORPROMAZINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
318.864 g/mol	0	2	4.9594	True

Structure

InChI

InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3

InChIKey

ZPEIMTDSQAKGNT-UHFFFAOYSA-N

Links

Gene (32 / 48)

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Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			ABCA1
BOSS	Text Mining			BBS9
BOSS	Text Mining			CAV3
BOSS	Text Mining			CDT1
BOSS	Text Mining			CPZ
BOSS	Text Mining			CYP2C8
BOSS	Text Mining			DDR2
BOSS	Text Mining			EPS15
BOSS	Text Mining			F3
BOSS	Text Mining			IL6
BOSS	Text Mining			KRIT1
BOSS	Text Mining			PRDX2
BOSS	Text Mining			PRL
BOSS	Text Mining			SLC7A1
BOSS	Text Mining			TACR2
BOSS	Text Mining			TNF
BOSS	Text Mining			TNFRSF13C
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	0.159	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	0.398	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	Potency	uM	15.849	IDH1	-	GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.601	NR1H4	-	GI(Protien) :
PubChem	Potency	uM	10.000	TDP1	-	GI(Protien) :
PubChem	Potency	uM	11.220	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
PubChem	Potency	uM	12.589	THPO	-	GI(Protien) :
PubChem	Potency	uM	10.000	TP53	-	GI(Protien) :
ChEMBL	AC50	nM	3981.070	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1000.000	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	398.110	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	158.500	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	398.100	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	158.490	CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	12589.300	THPO	-	Target : CHEMBL1293256
ChEMBL	Potency	nM	10000.000	TP53	-	Target : CHEMBL4096

Download gene sets

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