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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : Boss - unii-80168379ag

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Collection	D4 : Boss
Chemical Name	unii-80168379ag ( From PubChem : DOXORUBICIN )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Approved Approved Approved Approved Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 543.519 g/mol 6 12 0.7016 False(1/4)
Structure
InChI	InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1
InChIKey	AOJJSUZBOXZQNB-TZSSRYMLSA-N
Links
Gene (200 / 208) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining ABCA1 BOSS Text Mining ABCC2 BOSS Text Mining ABCC3 BOSS Text Mining ABCG2 BOSS Text Mining ACE BOSS Text Mining ACSM3 BOSS Text Mining ADAM17 BOSS Text Mining ADM BOSS Text Mining AFP BOSS Text Mining AKR1B1 BOSS Text Mining ALB BOSS Text Mining ALDH1B1 BOSS Text Mining APP BOSS Text Mining ASRGL1 BOSS Text Mining ATM BOSS Text Mining ATN1 BOSS Text Mining ATP1A3 BOSS Text Mining ATP1B1 BOSS Text Mining ATP8A2 BOSS Text Mining ATR BOSS Text Mining AURKB BOSS Text Mining AURKC BOSS Text Mining BAX BOSS Text Mining BBC3 BOSS Text Mining BCL2 BOSS Text Mining BCL2L1 BOSS Text Mining BCL6 BOSS Text Mining BECN1 BOSS Text Mining BRCA1 BOSS Text Mining C7orf49 BOSS Text Mining CASP3 BOSS Text Mining CASP8 BOSS Text Mining CASP9 BOSS Text Mining CAV3 BOSS Text Mining CBL BOSS Text Mining CBR1 BOSS Text Mining CBX8 BOSS Text Mining CCNB1 BOSS Text Mining CD24 BOSS Text Mining CD34 BOSS Text Mining CD4 BOSS Text Mining CD44 BOSS Text Mining CD79A BOSS Text Mining CD8A BOSS Text Mining CDC123 BOSS Text Mining CDH2 BOSS Text Mining CDK1 BOSS Text Mining CDK2 BOSS Text Mining CDK4 BOSS Text Mining CDKN2A BOSS Text Mining CDT1 BOSS Text Mining CEBPZ BOSS Text Mining CHEK1 BOSS Text Mining CHEK2 BOSS Text Mining CSF2 BOSS Text Mining CSF3 BOSS Text Mining CSH1 BOSS Text Mining CYCS BOSS Text Mining CYGB BOSS Text Mining CYLD BOSS Text Mining CYP2B6 BOSS Text Mining CYP2C8 BOSS Text Mining DAND5 BOSS Text Mining DDR2 BOSS Text Mining DDX53 BOSS Text Mining DECR1 BOSS Text Mining DES BOSS Text Mining DHFR BOSS Text Mining DNTT BOSS Text Mining DSC2 BOSS Text Mining EGF BOSS Text Mining EGFR BOSS Text Mining ELF3 BOSS Text Mining EPHB2 BOSS Text Mining ERBB2 BOSS Text Mining ERBB2 BOSS Text Mining EREG BOSS Text Mining ESR1 BOSS Text Mining ETFB BOSS Text Mining F3 BOSS Text Mining FAM126A BOSS Text Mining FANCC BOSS Text Mining FLT1 BOSS Text Mining FLT4 BOSS Text Mining FN1 BOSS Text Mining FOXO3 BOSS Text Mining GCK BOSS Text Mining GINS1 BOSS Text Mining GPR182 BOSS Text Mining GPX1 BOSS Text Mining GSTK1 BOSS Text Mining H2AFX BOSS Text Mining HBA1 BOSS Text Mining HBB BOSS Text Mining HDAC2 BOSS Text Mining HEBP1 BOSS Text Mining HMOX1 BOSS Text Mining HRAS BOSS Text Mining HSD17B1 BOSS Text Mining HSPA5 BOSS Text Mining HSPB2 BOSS Text Mining IDE BOSS Text Mining IFNA17 BOSS Text Mining IGFBP1 BOSS Text Mining IL4 BOSS Text Mining IL6 BOSS Text Mining INHA BOSS Text Mining INS BOSS Text Mining IRF4 BOSS Text Mining ISYNA1 BOSS Text Mining KIT BOSS Text Mining LDHA BOSS Text Mining LYZ BOSS Text Mining MAP1LC3A BOSS Text Mining MAPK3 BOSS Text Mining MCL1 BOSS Text Mining MMP2 BOSS Text Mining MMP9 BOSS Text Mining MMVP1 BOSS Text Mining MTOR BOSS Text Mining MUC16 BOSS Text Mining MYC BOSS Text Mining MYCN BOSS Text Mining NFKB1 BOSS Text Mining NFKB2 BOSS Text Mining NFYA BOSS Text Mining NLRP2 BOSS Text Mining NOC2L BOSS Text Mining NPHS1 BOSS Text Mining NPHS2 BOSS Text Mining NR4A1 BOSS Text Mining NSG1 BOSS Text Mining OPTN BOSS Text Mining PAK3 BOSS Text Mining PARP2 BOSS Text Mining PAX3 BOSS Text Mining PCNA BOSS Text Mining PGP BOSS Text Mining PGR BOSS Text Mining PLXNA3 BOSS Text Mining POLD4 BOSS Text Mining PPARG BOSS Text Mining PR@ BOSS Text Mining PRDX2 BOSS Text Mining PRRT2 BOSS Text Mining PTEN BOSS Text Mining PTK2B BOSS Text Mining RBP3 BOSS Text Mining REXO1L1P BOSS Text Mining RNASEH2A BOSS Text Mining ROCK1 BOSS Text Mining ROS1 BOSS Text Mining RPN2 BOSS Text Mining SART3 BOSS Text Mining SCARNA5 BOSS Text Mining SERPINA1 BOSS Text Mining SETD2 BOSS Text Mining SH3PXD2A BOSS Text Mining SIRT1 BOSS Text Mining SLC22A3 BOSS Text Mining SLC25A16 BOSS Text Mining SLC25A20 BOSS Text Mining SLC26A1 BOSS Text Mining SLC7A1 BOSS Text Mining SMUG1 BOSS Text Mining SOD1 BOSS Text Mining SOX2 BOSS Text Mining STAT3 BOSS Text Mining TACR2 BOSS Text Mining TAOK1 BOSS Text Mining TAS2R62P BOSS Text Mining TAT BOSS Text Mining TCOF1 BOSS Text Mining TGM2 BOSS Text Mining THM BOSS Text Mining TIMM8A BOSS Text Mining TNF BOSS Text Mining TNFRSF10B BOSS Text Mining TNFRSF8 BOSS Text Mining TNFSF10 BOSS Text Mining TOP2A BOSS Text Mining TP53 BOSS Text Mining TP73 BOSS Text Mining TRAF3 BOSS Text Mining TRAPPC9 BOSS Text Mining TSC1 BOSS Text Mining TUBE1 BOSS Text Mining TWIST1 BOSS Text Mining USO1 BOSS Text Mining VEGFA BOSS Text Mining VIM BOSS Text Mining WLS BOSS Text Mining XIAP BOSS Text Mining YWHAG PubChem Potency uM 26.680 POLK - GI(Protien) : PubChem None uM STK33 - GI(Protien) : ChEMBL Inhibition - ABCC3 - Target : CHEMBL5918 ChEMBL Inhibition - CYP1A2 - Target : CHEMBL3356 ChEMBL Inhibition - CYP2C19 - Target : CHEMBL3622 ChEMBL Inhibition - CYP2C9 - Target : CHEMBL3397 ChEMBL Inhibition - CYP2D6 - Target : CHEMBL289 ChEMBL Inhibition - TOP1 - Target : CHEMBL1781 ChEMBL Activity - TOP1 - Target : CHEMBL1781 ChEMBL Activity - TOP1 - Target : CHEMBL1781 ChEMBL Activity - TOP1 - Target : CHEMBL1781 ChEMBL Activity - TOP2A - Target : CHEMBL1806 ChEMBL Inhibition - TOP2A - Target : CHEMBL1806 ChEMBL Inhibition - TOP2A - Target : CHEMBL1806
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