Tan Lab | DSigDB

Gene Set: D4 : Boss - unii-00fn6ih15d

Collection

D4 : Boss

Chemical Name

unii-00fn6ih15d ( From PubChem : NORTRIPTYLINE HYDROCHLORIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
299.838 g/mol	2	1	5.0193	False(3/4)

Structure

InChI

InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H

InChIKey

Links

Gene (20 / 25)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			CYP2C8
BOSS	Text Mining			DDR2
BOSS	Text Mining			HTT
BOSS	Text Mining			TNF
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.314	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.603	AR	-	GI(Protien) :
PubChem	None	uM		CHRM1	-	GI(Protien) :
PubChem	None	uM		CHRM4	-	GI(Protien) :
PubChem	None	uM		CHRM5	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	Potency	uM	6.310	GLP1R	-	GI(Protien) :
PubChem	Potency	uM	23.109	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	7.943	KCNH2		GI(Protien) :
PubChem	Potency	uM	7.943	KCNH2		GI(Protien) :
PubChem	None	uM		KCNQ1	-	GI(Protien) :
PubChem	None	uM		KCNQ1	-	GI(Protien) :
PubChem	None	uM		MLLT3	-	GI(Protien) :
PubChem	None	uM		PLCG1	-	GI(Protien) :
PubChem	Potency	uM	9.200	TDP1	-	GI(Protien) :
PubChem	Potency	uM	14.963	TDP1	-	GI(Protien) :
PubChem	Potency	uM	20.596	TDP1	-	GI(Protien) :

Download gene sets