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Gene Set: D4 : Boss - uccf 031

Collection D4 : Boss
Chemical Name uccf 031 ( From PubChem : APIGENIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
270.237 g/mol 3 5 2.5768 True
Structure
InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
InChIKey KZNIFHPLKGYRTM-UHFFFAOYSA-N
Links

Gene (97 / 149)


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Source Type Unit Value Gene PMID Assay Other
BOSSText MiningAATF
BOSSText MiningABCA1
BOSSText MiningACHE
BOSSText MiningALB
BOSSText MiningATP8A2
BOSSText MiningAURKB
BOSSText MiningBBS9
BOSSText MiningBCL2
BOSSText MiningBCL2L1
BOSSText MiningCASP3
BOSSText MiningCASP8
BOSSText MiningCASP9
BOSSText MiningCBX8
BOSSText MiningCDK1
BOSSText MiningCDT1
BOSSText MiningCYCS
BOSSText MiningCYGB
BOSSText MiningCYP2C8
BOSSText MiningEPHB2
BOSSText MiningESR1
BOSSText MiningGLI2
BOSSText MiningGPR182
BOSSText MiningGPX1
BOSSText MiningHEBP1
BOSSText MiningICAM1
BOSSText MiningIL6
BOSSText MiningINS
BOSSText MiningISYNA1
BOSSText MiningLCN1
BOSSText MiningMAPK3
BOSSText MiningMCL1
BOSSText MiningMMP9
BOSSText MiningNFKB2
BOSSText MiningNSG1
BOSSText MiningOPTN
BOSSText MiningPARP2
BOSSText MiningPCNA
BOSSText MiningPGP
BOSSText MiningPOLD4
BOSSText MiningPPARG
BOSSText MiningPRRT2
BOSSText MiningPTK2B
BOSSText MiningPTPN1
BOSSText MiningREXO1L1P
BOSSText MiningRNASEH2A
BOSSText MiningROS1
BOSSText MiningSLC7A1
BOSSText MiningSTAT3
BOSSText MiningTAOK1
BOSSText MiningTCOF1
BOSSText MiningTNF
BOSSText MiningTNFRSF10B
BOSSText MiningTP53
BOSSText MiningTYR
BOSSText MiningVCAM1
BOSSText MiningVEGFA
BOSSText MiningXDH
PubChem AhR Potency (uM)uM21.977AHR-GI(Protien) :
PubChem NoneuMAKR1C4-GI(Protien) :
PubChem PotencyuM1.778ALDH1A1-GI(Protien) :
PubChem PotencyuM5.012ALOX15-GI(Protien) :
PubChem Ratio Potency (uM)uM37.435AR-GI(Protien) :
PubChem Ratio Potency (uM)uM46.861AR-GI(Protien) :
PubChem PotencyuM22.387BRCA1-GI(Protien) :
PubChem NoneuMCLK3-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM7.943CYP2C19-GI(Protien) :
PubChem NoneuMCYP2C19-GI(Protien) :
PubChem PotencyuM1.259CYP3A4-GI(Protien) :
PubChem PotencyuM3.162CYP3A4-GI(Protien) :
PubChem PotencyuM7.943CYP3A4-GI(Protien) :
PubChem NoneuMCYP3A4-GI(Protien) :
PubChem PotencyuM3.981ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM7.867ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM9.771ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM10.291ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM10.963ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM10.965ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM41.205ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM54.483ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM61.940ESR1-GI(Protien) :
PubChem NoneuMGEM-GI(Protien) :
PubChem NoneuMGNAI1-GI(Protien) :
PubChem EC50_uMuM49.490GSK3B-GI(Protien) :
PubChem PotencyuM12.589HIF1A-GI(Protien) :
PubChem PotencyuM3.548HPGD-GI(Protien) :
PubChem PotencyuM31.623HPGD-GI(Protien) :
PubChem NoneuMIL1B-GI(Protien) :
PubChem PotencyuM15.849MAPT-GI(Protien) :
PubChem Ratio Potency (uM)uM22.837NFE2L2-GI(Protien) :
PubChem PotencyuM24.337NFE2L2-GI(Protien) :
PubChem PotencyuM33.492NFE2L2-GI(Protien) :
PubChem PotencyuM25.119NPSR1-GI(Protien) :
PubChem NoneuMNR0B1-GI(Protien) :
PubChem PotencyuM44.668NR1H4-GI(Protien) :
PubChem NoneuMNR1H4-GI(Protien) :
PubChem Potency-Replicate_1uM31.623NR1I2-GI(Protien) :
PubChem Potency-Replicate_1uM44.668NR1I2-GI(Protien) :
PubChem Potency-Replicate_1uM27.539NR3C1-GI(Protien) :
PubChem Potency-Replicate_1uM27.913NR3C1-GI(Protien) :
PubChem PotencyuM31.623NR3C1-GI(Protien) :
PubChem PotencyuM3.264PARK2-GI(Protien) :
PubChem PotencyuM16.360PARK2-GI(Protien) :
PubChem NoneuMPIM1-GI(Protien) :
PubChem NoneuMPIM2-GI(Protien) :
PubChem PotencyuM19.953POLK-GI(Protien) :
PubChem Potency-Replicate_1uM17.376PPARD-GI(Protien) :
PubChem Potency-Replicate_1uM21.875PPARG-GI(Protien) :
PubChem PotencyuM44.668PPARG-GI(Protien) :
PubChem NoneuMPPARG-GI(Protien) :
PubChem NoneuMRGS12-GI(Protien) :
PubChem NoneuMSENP6-GI(Protien) :
PubChem NoneuMSENP6-GI(Protien) :
PubChem NoneuMSENP7-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem PotencyuM14.125SMN2-GI(Protien) :
PubChem PotencyuM22.387SMN2-GI(Protien) :
PubChem NoneuMSTK16-GI(Protien) :
PubChem PotencyuM5.173TDP1-GI(Protien) :
PubChem PotencyuM12.995TDP1-GI(Protien) :
PubChem Potency-Replicate_1uM48.972VDR-GI(Protien) :
PubChem NoneuMVDR-GI(Protien) :
ChEMBLPotencynM1778.300ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM5011.900ALOX15
-Target : CHEMBL2903
ChEMBLInhibition-CYBB
-Target : CHEMBL1287627
ChEMBLInhibition-CYBB
-Target : CHEMBL1287627
ChEMBLInhibition-CYBB
-Target : CHEMBL1287627
ChEMBLInhibition-CYBB
-Target : CHEMBL1287627
ChEMBLAC50nM63.100CYP1A2
-Target : CHEMBL3356
ChEMBLAC50nM125.890CYP1A2
-Target : CHEMBL3356
ChEMBLAC50nM7943.280CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM7943.300CYP2C19
-Target : CHEMBL3622
ChEMBLAC50nM1258.930CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM3162.300CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM7943.300CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM1258.900CYP3A4
-Target : CHEMBL340
ChEMBLAC50nM3162.280CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM12589.300HIF1A
-Target : CHEMBL4261
ChEMBLPotencynM31622.800HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM3548.100HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM398.100HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM11220.200KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM15848.900MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM25118.900NPSR1
-Target : CHEMBL5162
ChEMBLPotencynM22387.200SMN1; SMN2
-Target : CHEMBL1293232
ChEMBLPotencynM14125.400SMN1; SMN2
-Target : CHEMBL1293232
Download gene sets gmt, text, Detailed text
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Aurora, CO 80045, USA

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