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Gene Set: D4 : Boss - thiulin

Collection D4 : Boss
Chemical Name thiulin ( From PubChem : THIRAM )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotApprovedNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
240.433 g/mol 0 6 2.0608 True
Structure
InChI InChI=1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3
InChIKey KUAZQDVKQLNFPE-UHFFFAOYSA-N
Links

Gene (55 / 102)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
BOSSText MiningACHE
BOSSText MiningCYGB
BOSSText MiningCYP2B6
BOSSText MiningCYP2C8
BOSSText MiningDDT
BOSSText MiningGPX1
BOSSText MiningHBB
BOSSText MiningHLP
BOSSText MiningKRT5
BOSSText MiningKRT6B
BOSSText MiningLDHA
BOSSText MiningPALLD
BOSSText MiningSARS2
BOSSText MiningSLC7A1
PubChem PotencyuM0.079ALDH1A1-GI(Protien) :
PubChem PotencyuM0.126ALDH1A1-GI(Protien) :
PubChem PotencyuM0.501ALDH1A1-GI(Protien) :
PubChem NoneuMAPP-GI(Protien) :
PubChem Potency-Replicate_1uM0.061AR-GI(Protien) :
PubChem Potency-Replicate_1uM0.170AR-GI(Protien) :
PubChem PotencyuM2.512ATXN2-GI(Protien) :
PubChem IC50uMCACNA1B-GI(Protien) :
PubChem Potency-Replicate_1uM0.015CYP19A1-GI(Protien) :
PubChem Potency-Replicate_1uM0.048CYP19A1-GI(Protien) :
PubChem Potency-Replicate_1uM0.188CYP19A1-GI(Protien) :
PubChem PotencyuM15.849CYP3A4-GI(Protien) :
PubChem NoneuMDRD3-GI(Protien) :
PubChem PotencyuM1.122EHMT2-GI(Protien) :
PubChem PotencyuM1.259EHMT2-GI(Protien) :
PubChem PotencyuM39.811GAPDH-GI(Protien) :
PubChem NoneuMGAPDH-GI(Protien) :
PubChem PotencyuM1.334GMNN-GI(Protien) :
PubChem PotencyuM21.136GMNN-GI(Protien) :
PubChem NoneuMGNAI1-GI(Protien) :
PubChem PotencyuM0.708HPGD-GI(Protien) :
PubChem PotencyuM1.000HPGD-GI(Protien) :
PubChem AC50_uMuM7.741HSP90AA1-GI(Protien) :
PubChem Ratio Potency (uM)uM0.138HSPB1-GI(Protien) :
PubChem Ratio Potency (uM)uM0.188HSPB1-GI(Protien) :
PubChem PotencyuM1.000HTT-GI(Protien) :
PubChem NoneuMINS-GI(Protien) :
PubChem IC50uM0.223JAK2-GI(Protien) :
PubChem irf1 Inhibition [Ba/F3 cells] (IC50)uM2.375JAK2-GI(Protien) :
PubChem irf1 Inhibition [HEL cells] (IC50)uM13.470JAK2-GI(Protien) :
PubChem NoneuMJAK2-GI(Protien) :
PubChem NoneuMJAK2-GI(Protien) :
PubChem NoneuMJAK2-GI(Protien) :
PubChem PotencyuM14.125KAT2A-GI(Protien) :
PubChem PotencyuM31.623KAT2A-GI(Protien) :
PubChem PotencyuM44.668KCNH2GI(Protien) :
PubChem PotencyuM44.668KCNH2GI(Protien) :
PubChem NoneuMKCNQ1-GI(Protien) :
PubChem NoneuMMAP1LC3A-GI(Protien) :
PubChem Mean Mutant EC50uM0.080MDM2-GI(Protien) :
PubChem EC50uM0.180MDM2-GI(Protien) :
PubChem Mean Wild-type EC50uM0.400MDM2-GI(Protien) :
PubChem NoneuMMDM2-GI(Protien) :
PubChem Potency-Replicate_1uM42.163NFE2L2-GI(Protien) :
PubChem NoneuMNFKBIA-GI(Protien) :
PubChem NoneuMNLRP1-GI(Protien) :
PubChem NoneuMNR2E3-GI(Protien) :
PubChem Ratio Potency (uM)uM0.061NR3C1-GI(Protien) :
PubChem Ratio Potency (uM)uMNR3C1-GI(Protien) :
PubChem PotencyuM14.125PKM-GI(Protien) :
PubChem PotencyuM0.336PLK1-GI(Protien) :
PubChem Ratio Potency (uM)uM0.206PPARD-GI(Protien) :
PubChem Ratio Potency (uM)uM1.100PPARD-GI(Protien) :
PubChem NoneuMPRMT1-GI(Protien) :
PubChem NoneuMPRMT1-GI(Protien) :
PubChem NoneuMPTGER2-GI(Protien) :
PubChem NoneuMRGS12-GI(Protien) :
PubChem PotencyuM44.668RXRA-GI(Protien) :
PubChem NoneuMSELE-GI(Protien) :
PubChem NoneuMSMARCA2-GI(Protien) :
PubChem PotencyuM0.009TDP1-GI(Protien) :
PubChem PotencyuM0.130TDP1-GI(Protien) :
PubChem PotencyuM0.133TDP1-GI(Protien) :
PubChem PotencyuM0.133TDP1-GI(Protien) :
PubChem PotencyuM0.146TDP1-GI(Protien) :
PubChem PotencyuM0.146TDP1-GI(Protien) :
PubChem PotencyuM2.512VDR-GI(Protien) :
PubChem PotencyuM11.220VDR-GI(Protien) :
ChEMBLPotencynM79.400ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM125.900ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM501.200ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM15848.900CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM1258.900EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM1122.000EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM39810.700GAPDH
-Target : CHEMBL2284
ChEMBLPotencynM707.900HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM1000.000HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM12589.300HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM50.100HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM1000.000HTT
-Target : CHEMBL5514
ChEMBLActivityum2.380JAK2
-Target : CHEMBL2971
ChEMBLActivityum13.470JAK2
-Target : CHEMBL2971
ChEMBLIC50nM223.000JAK2
-Target : CHEMBL2971
ChEMBLPotencynM14125.400KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM31622.800KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM25118.900KDM4E
-Target : CHEMBL1293226
ChEMBLEC50nM180.000MDM2
-Target : CHEMBL5023
ChEMBLPotencynM14125.400PKM
-Target : CHEMBL1075189
Download gene sets gmt, text, Detailed text
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