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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : Boss - tetraiodothyronine

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Collection	D4 : Boss
Chemical Name	tetraiodothyronine ( From PubChem : L-THYROXINE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Approved Not Approved Approved Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 776.87 g/mol 3 5 5.2576 False(2/4)
Structure
InChI	InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1
InChIKey	XUIIKFGFIJCVMT-LBPRGKRZSA-N
Links
Gene (201 / 208) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining AATF BOSS Text Mining ABCA1 BOSS Text Mining ABCC10 BOSS Text Mining ACE BOSS Text Mining ACHE BOSS Text Mining AKR1B1 BOSS Text Mining ALB BOSS Text Mining ATM BOSS Text Mining ATN1 BOSS Text Mining ATP8A2 BOSS Text Mining AURKB BOSS Text Mining AWAT2 BOSS Text Mining BCL2 BOSS Text Mining BDNF-AS BOSS Text Mining BRD2 BOSS Text Mining C7orf49 BOSS Text Mining CASP3 BOSS Text Mining CBL BOSS Text Mining CD34 BOSS Text Mining CD4 BOSS Text Mining CD55 BOSS Text Mining CD68 BOSS Text Mining CD8A BOSS Text Mining CDH2 BOSS Text Mining CDKN2A BOSS Text Mining CDT1 BOSS Text Mining CEACAM1 BOSS Text Mining CEACAM3 BOSS Text Mining CFB BOSS Text Mining CKAP4 BOSS Text Mining CNC2 BOSS Text Mining COG3 BOSS Text Mining CSF2 BOSS Text Mining CXCL10 BOSS Text Mining CXCR1 BOSS Text Mining CYCS BOSS Text Mining CYGB BOSS Text Mining CYLD BOSS Text Mining CYP2B6 BOSS Text Mining CYP2C8 BOSS Text Mining DAND5 BOSS Text Mining DDR2 BOSS Text Mining DECR1 BOSS Text Mining DES BOSS Text Mining DIDO1 BOSS Text Mining DIO3 BOSS Text Mining DLD BOSS Text Mining DUOX2 BOSS Text Mining EGF BOSS Text Mining EGFR BOSS Text Mining ELF3 BOSS Text Mining ELL BOSS Text Mining ENO1 BOSS Text Mining EPHB2 BOSS Text Mining ERBB2 BOSS Text Mining EREG BOSS Text Mining ESR1 BOSS Text Mining ETFB BOSS Text Mining EVA1C BOSS Text Mining F3 BOSS Text Mining F9 BOSS Text Mining FAM109A BOSS Text Mining FGF13 BOSS Text Mining FLT1 BOSS Text Mining FN1 BOSS Text Mining FOXP3 BOSS Text Mining GAD2 BOSS Text Mining GCG BOSS Text Mining GCK BOSS Text Mining GGH BOSS Text Mining GJA1 BOSS Text Mining GLP1R BOSS Text Mining GNAS BOSS Text Mining GPX1 BOSS Text Mining GYPE BOSS Text Mining HBB BOSS Text Mining HPD BOSS Text Mining HRAS BOSS Text Mining HSD11B1 BOSS Text Mining HSD17B6 BOSS Text Mining ICOS BOSS Text Mining IFNA1 BOSS Text Mining IFNA17 BOSS Text Mining IFNAR1 BOSS Text Mining IGF1 BOSS Text Mining IGFBP1 BOSS Text Mining IGFBP3 BOSS Text Mining IGHD2-15 BOSS Text Mining IGLL1 BOSS Text Mining IGLL2P BOSS Text Mining IGLL3P BOSS Text Mining IL10 BOSS Text Mining IL2 BOSS Text Mining IL27 BOSS Text Mining IL4 BOSS Text Mining IL6 BOSS Text Mining INS BOSS Text Mining JUP BOSS Text Mining KDR BOSS Text Mining KIT BOSS Text Mining KRT19 BOSS Text Mining KRT5 BOSS Text Mining KRT6B BOSS Text Mining KRT7 BOSS Text Mining LDHA BOSS Text Mining LEP BOSS Text Mining LGALS2 BOSS Text Mining LNPEP BOSS Text Mining MAPK3 BOSS Text Mining MMP2 BOSS Text Mining MMP9 BOSS Text Mining MPO BOSS Text Mining MRS2 BOSS Text Mining MTOR BOSS Text Mining MTR BOSS Text Mining NCAM1 BOSS Text Mining NCOA4 BOSS Text Mining NDUFA5 BOSS Text Mining NELFCD BOSS Text Mining NKX2-1 BOSS Text Mining NONO BOSS Text Mining NR4A1 BOSS Text Mining NRAS BOSS Text Mining NSG1 BOSS Text Mining OPTN BOSS Text Mining PAGR1 BOSS Text Mining PAX8 BOSS Text Mining PCNA BOSS Text Mining PGR BOSS Text Mining PHF11 BOSS Text Mining PIK3CD BOSS Text Mining PITX1 BOSS Text Mining PLXNA3 BOSS Text Mining PNPLA3 BOSS Text Mining POLD4 BOSS Text Mining POMC BOSS Text Mining PPARG BOSS Text Mining PRG4 BOSS Text Mining PRL BOSS Text Mining PRRT2 BOSS Text Mining PTEN BOSS Text Mining PTH BOSS Text Mining PTK2B BOSS Text Mining PTPRC BOSS Text Mining REG3A BOSS Text Mining RHO BOSS Text Mining RNASEH2A BOSS Text Mining ROS1 BOSS Text Mining S100A1 BOSS Text Mining SCG2 BOSS Text Mining SERPINA7 BOSS Text Mining SETD2 BOSS Text Mining SHBG BOSS Text Mining SIL1 BOSS Text Mining SLC16A2 BOSS Text Mining SLC17A5 BOSS Text Mining SLC22A3 BOSS Text Mining SLC25A16 BOSS Text Mining SLC25A20 BOSS Text Mining SLC4A1 BOSS Text Mining SLC5A5 BOSS Text Mining SLC5A8 BOSS Text Mining SLC7A1 BOSS Text Mining SMUG1 BOSS Text Mining SOD1 BOSS Text Mining SST BOSS Text Mining STAT3 BOSS Text Mining SYP BOSS Text Mining TACR2 BOSS Text Mining TCOF1 BOSS Text Mining TCP1 BOSS Text Mining TENM1 BOSS Text Mining TG BOSS Text Mining TGM2 BOSS Text Mining THM BOSS Text Mining THRB BOSS Text Mining TMED1 BOSS Text Mining TNF BOSS Text Mining TP53 BOSS Text Mining TPCN1 BOSS Text Mining TPM3 BOSS Text Mining TRAPPC9 BOSS Text Mining TRH BOSS Text Mining TSC1 BOSS Text Mining TSHR BOSS Text Mining TSPAN1 BOSS Text Mining TTR BOSS Text Mining TXN BOSS Text Mining TYRP1 BOSS Text Mining USO1 BOSS Text Mining VEGFA BOSS Text Mining VIM BOSS Text Mining VIPR1 BOSS Text Mining ZHX2 PubChem None uM ABCB1 - GI(Protien) : PubChem Potency-Replicate_1 uM 13.771 AHR - GI(Protien) : PubChem AhR Potency (uM) uM 15.451 AHR - GI(Protien) : PubChem AhR Potency (uM) uM 23.710 AHR - GI(Protien) : PubChem Potency uM 44.668 AHR - GI(Protien) : PubChem None uM ATG4B - GI(Protien) : PubChem Potency uM 54.483 NFE2L2 - GI(Protien) : PubChem None uM NR3C1 - GI(Protien) : PubChem None uM PLA2G7 - GI(Protien) : PubChem None uM PLA2G7 - GI(Protien) : PubChem Potency uM 39.811 PPARG - GI(Protien) : PubChem None uM PPARG - GI(Protien) : PubChem None uM PPP1CA - GI(Protien) : PubChem Potency uM 0.010 THRB - GI(Protien) :
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