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Gene Set: D4 : Boss - sophoricol

Collection D4 : Boss
Chemical Name sophoricol ( From PubChem : GENISTEIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotApprovedNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
270.237 g/mol 3 5 2.5768 True
Structure
InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
InChIKey TZBJGXHYKVUXJN-UHFFFAOYSA-N
Links

Gene (143 / 202)


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Source Type Unit Value Gene PMID Assay Other
BOSSText MiningABCA1
BOSSText MiningABCC10
BOSSText MiningABCC2
BOSSText MiningABCC3
BOSSText MiningABCG2
BOSSText MiningACP1
BOSSText MiningAGT
BOSSText MiningAHR
BOSSText MiningAKR1B1
BOSSText MiningALB
BOSSText MiningAPEX1
BOSSText MiningATP1B1
BOSSText MiningATP8A2
BOSSText MiningAURKB
BOSSText MiningBBS9
BOSSText MiningBCL2
BOSSText MiningBRCA1
BOSSText MiningBTF3P11
BOSSText MiningCASP3
BOSSText MiningCASP8
BOSSText MiningCASP9
BOSSText MiningCAV3
BOSSText MiningCBL
BOSSText MiningCBX8
BOSSText MiningCCNB1
BOSSText MiningCD44
BOSSText MiningCDH2
BOSSText MiningCDK1
BOSSText MiningCDT1
BOSSText MiningCEACAM1
BOSSText MiningCHUK
BOSSText MiningCSN2
BOSSText MiningCXCL12
BOSSText MiningCYCS
BOSSText MiningCYGB
BOSSText MiningCYP2C8
BOSSText MiningDDR2
BOSSText MiningDECR1
BOSSText MiningEDN1
BOSSText MiningEGF
BOSSText MiningEGFR
BOSSText MiningELF3
BOSSText MiningEPHB2
BOSSText MiningERBB2
BOSSText MiningEREG
BOSSText MiningESR1
BOSSText MiningESR2
BOSSText MiningFN1
BOSSText MiningGEN1
BOSSText MiningGINS1
BOSSText MiningGPR182
BOSSText MiningGPX1
BOSSText MiningGYPE
BOSSText MiningHEBP1
BOSSText MiningHERC2
BOSSText MiningHMOX1
BOSSText MiningICAM1
BOSSText MiningIGFBP1
BOSSText MiningIL10
BOSSText MiningIL4
BOSSText MiningIL6
BOSSText MiningINS
BOSSText MiningIRF6
BOSSText MiningIRS4
BOSSText MiningISYNA1
BOSSText MiningKISS1
BOSSText MiningKRIT1
BOSSText MiningKRT10
BOSSText MiningLDHA
BOSSText MiningLEP
BOSSText MiningMAP3K1
BOSSText MiningMAPK3
BOSSText MiningMERTK
BOSSText MiningMID1
BOSSText MiningMMP2
BOSSText MiningMMP9
BOSSText MiningMPO
BOSSText MiningMPP2
BOSSText MiningNFKB1
BOSSText MiningNFKB2
BOSSText MiningNGF
BOSSText MiningNSG1
BOSSText MiningOPTN
BOSSText MiningPARP2
BOSSText MiningPCNA
BOSSText MiningPGP
BOSSText MiningPGR
BOSSText MiningPNPLA3
BOSSText MiningPOLD4
BOSSText MiningPOTEF
BOSSText MiningPPARG
BOSSText MiningPRDX2
BOSSText MiningPRG4
BOSSText MiningPRRT2
BOSSText MiningPTEN
BOSSText MiningPTGS1
BOSSText MiningPTK2B
BOSSText MiningRHO
BOSSText MiningRNASEH2A
BOSSText MiningRNY4
BOSSText MiningROCK1
BOSSText MiningROS1
BOSSText MiningRUNX2
BOSSText MiningSLC25A20
BOSSText MiningSLC2A4
BOSSText MiningSLC7A1
BOSSText MiningTAOK1
BOSSText MiningTAS2R62P
BOSSText MiningTLR4
BOSSText MiningTNF
BOSSText MiningTNFRSF10B
BOSSText MiningTNFSF11
BOSSText MiningTP53
BOSSText MiningTSC1
BOSSText MiningTYRP1
BOSSText MiningVCAM1
BOSSText MiningVEGFA
PubChem AhR Potency (uM)uM4.216AHR-GI(Protien) :
PubChem AhR Potency (uM)uM7.406AHR-GI(Protien) :
PubChem Potency-Replicate_1uM12.197AHR-GI(Protien) :
PubChem PotencyuM12.589AHR-GI(Protien) :
PubChem Ratio Potency (uM)uM24.131AR-GI(Protien) :
PubChem Ratio Potency (uM)uM34.665AR-GI(Protien) :
PubChem PotencyuM9.196ATAD5-GI(Protien) :
PubChem PotencyuM16.354ATAD5-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM19.953CYP2C19-GI(Protien) :
PubChem PotencyuM12.589CYP3A4-GI(Protien) :
PubChem NoneuMCYP3A4-GI(Protien) :
PubChem PotencyuM0.398ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM0.849ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM2.660ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM3.064ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM4.633ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM6.007ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM6.801ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM8.158ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM10.155ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM12.300ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM43.641ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM46.227ESR1-GI(Protien) :
PubChem PotencyuM15.849GBA-GI(Protien) :
PubChem NoneuMGEM-GI(Protien) :
PubChem PotencyuM19.953HPGD-GI(Protien) :
PubChem PotencyuM25.119HPGD-GI(Protien) :
PubChem NoneuMHPGD-GI(Protien) :
PubChem NoneuMITPKC-GI(Protien) :
PubChem Ratio Potency (uM)uM4.959NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM6.741NFE2L2-GI(Protien) :
PubChem PotencyuM9.688NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM10.590NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM11.296NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM11.882NFE2L2-GI(Protien) :
PubChem PotencyuM13.333NFE2L2-GI(Protien) :
PubChem PotencyuM5.805NPC1-GI(Protien) :
PubChem NoneuMNR0B1-GI(Protien) :
PubChem PotencyuM25.119NR1H4-GI(Protien) :
PubChem Potency-Replicate_1uM26.601NR1H4-GI(Protien) :
PubChem Potency-Replicate_1uM38.895NR1H4-GI(Protien) :
PubChem NoneuMNR1H4-GI(Protien) :
PubChem Potency-Replicate_1uM19.953NR1I2-GI(Protien) :
PubChem Potency-Replicate_1uM44.668NR1I2-GI(Protien) :
PubChem NoneuMNR3C1-GI(Protien) :
PubChem PotencyuM8.200PARK2-GI(Protien) :
PubChem NoneuMPIM2-GI(Protien) :
PubChem NoneuMPPARD-GI(Protien) :
PubChem Potency-Replicate_1uM38.895PPARG-GI(Protien) :
PubChem Potency-Replicate_1uM48.147PPARG-GI(Protien) :
PubChem NoneuMPPARG-GI(Protien) :
PubChem PotencyuM12.589RAB9A-GI(Protien) :
PubChem PotencyuM35.481RXRA-GI(Protien) :
PubChem NoneuMSMARCA2-GI(Protien) :
PubChem NoneuMSMARCA2-GI(Protien) :
PubChem PotencyuM22.387SMN2-GI(Protien) :
PubChem PotencyuM25.119SMN2-GI(Protien) :
PubChem PotencyuM28.184SMN2-GI(Protien) :
PubChem PotencyuM11.886TDP1-GI(Protien) :
PubChem PotencyuM13.336TDP1-GI(Protien) :
PubChem PotencyuM18.356TDP1-GI(Protien) :
PubChem PotencyuM1.585THPO-GI(Protien) :
PubChem PotencyuM10.000TP53-GI(Protien) :
ChEMBLPotencynM9196.200ATAD5
-Target : CHEMBL1741209
ChEMBLPotencynM16353.500ATAD5
-Target : CHEMBL1741209
ChEMBLAC50nM5011.870CYP1A2
-Target : CHEMBL3356
ChEMBLPotencynM19952.600CYP2C19
-Target : CHEMBL3622
ChEMBLAC50nM12589.200CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM12589.300CYP3A4
-Target : CHEMBL340
ChEMBLActivity-ESR1
-Target : CHEMBL206
ChEMBLActivity-ESR1
-Target : CHEMBL206
ChEMBLPotencynM15848.900GBA
-Target : CHEMBL2179
ChEMBLPotencynM19952.600HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM25118.900HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM5804.800NPC1
-Target : CHEMBL1293277
ChEMBLPotencynM12589.300RAB9A
-Target : CHEMBL1293294
ChEMBLPotencynM22387.200SMN1; SMN2
-Target : CHEMBL1293232
ChEMBLPotencynM25118.900SMN1; SMN2
-Target : CHEMBL1293232
ChEMBLPotencynM28183.800SMN1; SMN2
-Target : CHEMBL1293232
ChEMBLPotencynM1584.900THPO
-Target : CHEMBL1293256
ChEMBLActivity-TOP2A
-Target : CHEMBL1806
ChEMBLActivity-TOP2A
-Target : CHEMBL1806
ChEMBLPotencynM10000.000TP53
-Target : CHEMBL4096
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Aurora, CO 80045, USA

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