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Gene Set: D4 : Boss - prophenatin

Collection D4 : Boss
Chemical Name prophenatin ( From PubChem : DICLOFENAC )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedNotApprovedApprovedNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
296.149 g/mol 2 2 4.4371 True
Structure
InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)
InChIKey DCOPUUMXTXDBNB-UHFFFAOYSA-N
Links

Gene (59 / 76)


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Source Type Unit Value Gene PMID Assay Other
BOSSText MiningACHE
BOSSText MiningALB
BOSSText MiningALOX5
BOSSText MiningARSA
BOSSText MiningATP4A
BOSSText MiningATP8A2
BOSSText MiningBBS9
BOSSText MiningBCL2
BOSSText MiningCASP3
BOSSText MiningCASP9
BOSSText MiningCDT1
BOSSText MiningCOX8C
BOSSText MiningCYCS
BOSSText MiningCYGB
BOSSText MiningCYP2B6
BOSSText MiningCYP2C8
BOSSText MiningDDR2
BOSSText MiningDECR1
BOSSText MiningDLD
BOSSText MiningDSC2
BOSSText MiningF9
BOSSText MiningGPX1
BOSSText MiningGYPE
BOSSText MiningHBB
BOSSText MiningHK1
BOSSText MiningHLP
BOSSText MiningIL10
BOSSText MiningIL4
BOSSText MiningIL6
BOSSText MiningIRF6
BOSSText MiningKCNJ3
BOSSText MiningKSR1
BOSSText MiningLDHA
BOSSText MiningMMP3
BOSSText MiningMPO
BOSSText MiningNR4A3
BOSSText MiningOPTN
BOSSText MiningPPARG
BOSSText MiningPPIG
BOSSText MiningPTGS1
BOSSText MiningREXO1L1P
BOSSText MiningRHO
BOSSText MiningSLC25A20
BOSSText MiningSLC7A1
BOSSText MiningSPRR2A
BOSSText MiningTNF
BOSSText MiningTRAPPC9
BOSSText MiningTYRP1
BOSSText MiningUGT2B7
BOSSText MiningVTRNA1-1
PubChem Ratio Potency (uM)uM33.360AR-GI(Protien) :
PubChem PotencyuM1.585CYP2C9-GI(Protien) :
PubChem PotencyuM7.943CYP2C9-GI(Protien) :
PubChem NoneuMCYP2C9-GI(Protien) :
PubChem PotencyuM10.000CYP3A4-GI(Protien) :
PubChem Potency-Replicate_1uM0.001ESR1-GI(Protien) :
PubChem PotencyuM6.310HIF1A-GI(Protien) :
PubChem PotencyuM25.119HIF1A-GI(Protien) :
PubChem Potency-Replicate_1uM3.889PPARG-GI(Protien) :
PubChem Potency-Replicate_1uM11.882PPARG-GI(Protien) :
PubChem NoneuMPPARG-GI(Protien) :
PubChem NoneuMSLC5A7-GI(Protien) :
ChEMBLActivity-ALB
-Target : CHEMBL3253
ChEMBLInhibition-CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLAC50nM7943.280CYP2C9
-Target : CHEMBL3397
ChEMBLAC50nM1584.890CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM1584.900CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM7943.300CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM10000.000CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM25118.900HIF1A
-Target : CHEMBL4261
ChEMBLPotencynM6309.600HIF1A
-Target : CHEMBL4261
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