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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : Boss - 7,12-dimethylbenzanthracene

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Collection	D4 : Boss
Chemical Name	7,12-dimethylbenzanthracene ( From PubChem : DMBA )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 256.341 g/mol 0 0 5.763 False(3/4)
Structure
InChI	InChI=1S/C20H16/c1-13-16-8-5-6-9-17(16)14(2)20-18(13)12-11-15-7-3-4-10-19(15)20/h3-12H,1-2H3
InChIKey	ARSRBNBHOADGJU-UHFFFAOYSA-N
Links
Gene (39 / 61) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining ABCA1 BOSS Text Mining BCL2 BOSS Text Mining CASP3 BOSS Text Mining CDT1 BOSS Text Mining CYGB BOSS Text Mining CYP2C8 BOSS Text Mining GPX1 BOSS Text Mining LDHA BOSS Text Mining PCNA BOSS Text Mining PLAT BOSS Text Mining REXO1L1P BOSS Text Mining RNASEH2A BOSS Text Mining SLC7A1 BOSS Text Mining SOD1 BOSS Text Mining TP53 BOSS Text Mining TSC1 BOSS Text Mining VEGFA PubChem Potency-Replicate_1 uM 8.547 AHR - GI(Protien) : PubChem AhR Potency (uM) uM 9.776 AHR - GI(Protien) : PubChem AhR Potency (uM) uM 15.956 AHR - GI(Protien) : PubChem Potency-Replicate_1 uM 21.690 AHR - GI(Protien) : PubChem Potency uM 25.119 AHR - GI(Protien) : PubChem None uM APLNR - GI(Protien) : PubChem Potency-Replicate_1 uM 30.638 AR - GI(Protien) : PubChem Potency uM 18.349 ATAD5 - GI(Protien) : PubChem Potency-Replicate_1 uM 27.306 CYP19A1 - GI(Protien) : PubChem None uM CYP19A1 - GI(Protien) : PubChem None uM DRD2 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.068 ESR1 - GI(Protien) : PubChem ER Potency (uM) uM 0.486 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.486 ESR1 - GI(Protien) : PubChem Potency uM 4.467 ESR1 - GI(Protien) : PubChem Potency uM 15.849 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 30.327 ESR1 - GI(Protien) : PubChem ER Potency (uM) uM ESR1 - GI(Protien) : PubChem Potency uM 1.836 GMNN - GI(Protien) : PubChem Potency uM 44.668 HIF1A - GI(Protien) : PubChem Ratio Potency (uM) uM 47.548 HSPB1 - GI(Protien) : PubChem Ratio Potency (uM) uM 50.882 HSPB1 - GI(Protien) : PubChem None uM MDM2 - GI(Protien) : PubChem None uM MDM2 - GI(Protien) : PubChem None uM MDM4 - GI(Protien) : PubChem None uM MDM4 - GI(Protien) : PubChem Ratio Potency (uM) uM 6.859 NFE2L2 - GI(Protien) : PubChem Ratio Potency (uM) uM 7.473 NFE2L2 - GI(Protien) : PubChem Potency uM 10.591 NFE2L2 - GI(Protien) : PubChem Potency uM 24.337 NFE2L2 - GI(Protien) : PubChem None uM NLRP3 - GI(Protien) : PubChem None uM NLRP3 - GI(Protien) : PubChem Potency-Replicate_1 uM 48.469 NR1H4 - GI(Protien) : PubChem Potency-Replicate_1 uM 39.811 NR1I2 - GI(Protien) : PubChem Potency-Replicate_1 uM 3.850 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 28.871 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 48.966 NR3C1 - GI(Protien) : PubChem None uM OPRD1 - GI(Protien) : PubChem None uM OPRM1 - GI(Protien) : PubChem Ratio Potency (uM) uM 11.168 PPARG - GI(Protien) : PubChem Potency uM 8.912 RXRA - GI(Protien) : ChEMBL Potency nM 18348.900 ATAD5 - Target : CHEMBL1741209 ChEMBL Potency nM 44668.400 HIF1A - Target : CHEMBL4261 ChEMBL Potency nM 25118.900 HSD17B10 - Target : CHEMBL4159
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