Tan Lab | DSigDB

Gene Set: D4 : Boss - pfizer b 174987

Collection

D4 : Boss

Chemical Name

pfizer b 174987 ( From PubChem : BREFELDIN A )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
280.359 g/mol	2	4	1.9624	True

Structure

InChI

InChI=1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3/b6-4+,8-7+/t11-,12+,13-,14+,15+/m0/s1

InChIKey

KQNZDYYTLMIZCT-KQPMLPITSA-N

Links

Gene (70 / 91)

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Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			ABCA1
BOSS	Text Mining			APP
BOSS	Text Mining			ARF1
BOSS	Text Mining			ARF6
BOSS	Text Mining			ATF6
BOSS	Text Mining			ATP1B1
BOSS	Text Mining			ATP8A2
BOSS	Text Mining			CASP3
BOSS	Text Mining			CD4
BOSS	Text Mining			CDKN2A
BOSS	Text Mining			CDT1
BOSS	Text Mining			CEBPZ
BOSS	Text Mining			CRELD2
BOSS	Text Mining			F3
BOSS	Text Mining			GJA1
BOSS	Text Mining			HK1
BOSS	Text Mining			HPD
BOSS	Text Mining			HSPA5
BOSS	Text Mining			IFNA1
BOSS	Text Mining			IL10
BOSS	Text Mining			IL5
BOSS	Text Mining			IL6
BOSS	Text Mining			INS
BOSS	Text Mining			JAK2
BOSS	Text Mining			KCNJ2
BOSS	Text Mining			KDR
BOSS	Text Mining			LEP
BOSS	Text Mining			MAPK3
BOSS	Text Mining			MTG1
BOSS	Text Mining			OPTN
BOSS	Text Mining			P2RY2
BOSS	Text Mining			PRDX2
BOSS	Text Mining			PTGES2
BOSS	Text Mining			PTK2B
BOSS	Text Mining			RAB1A
BOSS	Text Mining			RAB7A
BOSS	Text Mining			RASGRF1
BOSS	Text Mining			RNASEH2A
BOSS	Text Mining			SAR1A
BOSS	Text Mining			SGK1
BOSS	Text Mining			SLC25A20
BOSS	Text Mining			SLC5A1
BOSS	Text Mining			SLC6A19
BOSS	Text Mining			TFAP2A
BOSS	Text Mining			TNF
BOSS	Text Mining			TRAPPC9
BOSS	Text Mining			WDTC1
BOSS	Text Mining			XBP1P1
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	Potency	uM	0.651	GMNN	-	GI(Protien) :
PubChem	None	uM		HIF1A	-	GI(Protien) :
PubChem	Potency	uM	0.058	IDH1	-	GI(Protien) :
PubChem	Potency	uM	0.411	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	Potency	uM	0.231	NFE2L2	-	GI(Protien) :
PubChem	IC50	uM	0.134	NR0B1	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		OPRD1	-	GI(Protien) :
PubChem	None	uM		OPRM1	-	GI(Protien) :
PubChem	AC50_uM	uM	0.260	PAX8	-	GI(Protien) :
PubChem	None	uM		PAX8	-	GI(Protien) :
PubChem	IC50	uM	3.505	PRNP	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	Potency	uM	0.058	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.116	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.126	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.015	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.073	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.651	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	231.100	NFE2L2	-	Target : CHEMBL1075094

Download gene sets

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