Tan Lab | DSigDB

Gene Set: D4 : Boss - paxpar

Collection

D4 : Boss

Chemical Name

paxpar ( From PubChem : PAROXETINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
329.365 g/mol	1	4	3.6553	True

Structure

InChI

InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1

InChIKey

Links

Gene (24 / 28)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			ACHE
BOSS	Text Mining			BBS9
BOSS	Text Mining			BDNF-AS
BOSS	Text Mining			C7orf49
BOSS	Text Mining			CD52
BOSS	Text Mining			CDT1
BOSS	Text Mining			CYGB
BOSS	Text Mining			CYP2B6
BOSS	Text Mining			CYP2C8
BOSS	Text Mining			DDR2
BOSS	Text Mining			HLP
BOSS	Text Mining			HTR2A
BOSS	Text Mining			HTR4
BOSS	Text Mining			HTT
BOSS	Text Mining			ISYNA1
BOSS	Text Mining			MAOB
BOSS	Text Mining			P2RY2
BOSS	Text Mining			PPIG
BOSS	Text Mining			SLC6A3
PubChem	Potency-Replicate_1	uM	13.448	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.132	AR	-	GI(Protien) :
PubChem	Potency	uM	35.481	ATXN2	-	GI(Protien) :
PubChem	Potency	uM	23.778	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	2.931	MTOR	-	GI(Protien) :
PubChem	Potency	uM	9.441	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.789	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	23778.100	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	2930.900	MTOR	-	Target : CHEMBL2842

Download gene sets