DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

Home

Search Gene

Collection

Browse

Download

Help

DSigDB Home

Search Gene

Collections

Browse Gene Sets

Download

Help

Gene Set: D4 : Boss - n-acetyl-5-methoxy-tryptamine

---

Collection	D4 : Boss
Chemical Name	n-acetyl-5-methoxy-tryptamine ( From PubChem : MELATONIN )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Approved Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 232.278 g/mol 2 3 2.246 True
Structure
InChI	InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
InChIKey	DRLFMBDRBRZALE-UHFFFAOYSA-N
Links
Gene (184 / 188) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining AANAT BOSS Text Mining AATF BOSS Text Mining ABCA1 BOSS Text Mining ACHE BOSS Text Mining ACO1 BOSS Text Mining AKR1B1 BOSS Text Mining ALB BOSS Text Mining APP BOSS Text Mining ARHGEF7 BOSS Text Mining ARNTL BOSS Text Mining ASMT BOSS Text Mining ATP1B1 BOSS Text Mining ATP8A2 BOSS Text Mining AURKB BOSS Text Mining BAX BOSS Text Mining BBS9 BOSS Text Mining BCL2 BOSS Text Mining BCL2L1 BOSS Text Mining BDNF-AS BOSS Text Mining BECN1 BOSS Text Mining BRD2 BOSS Text Mining C7orf49 BOSS Text Mining CA3 BOSS Text Mining CASP3 BOSS Text Mining CASP9 BOSS Text Mining CCK BOSS Text Mining CD4 BOSS Text Mining CD8A BOSS Text Mining CDK1 BOSS Text Mining CDT1 BOSS Text Mining CEACAM1 BOSS Text Mining CEBPZ BOSS Text Mining CLOCK BOSS Text Mining CRY1 BOSS Text Mining CRY2 BOSS Text Mining CXXC1 BOSS Text Mining CYCS BOSS Text Mining CYGB BOSS Text Mining CYP2B6 BOSS Text Mining CYP2C8 BOSS Text Mining CYSLTR2 BOSS Text Mining DDAH2 BOSS Text Mining DDC BOSS Text Mining DDR2 BOSS Text Mining DECR1 BOSS Text Mining DHFR BOSS Text Mining DIO3 BOSS Text Mining EDN1 BOSS Text Mining EGF BOSS Text Mining EP300 BOSS Text Mining EPHB2 BOSS Text Mining ERBB2 BOSS Text Mining EREG BOSS Text Mining ESR1 BOSS Text Mining EYA3 BOSS Text Mining FAM109A BOSS Text Mining FCGR3A BOSS Text Mining GCG BOSS Text Mining GCH1 BOSS Text Mining GFAP BOSS Text Mining GGH BOSS Text Mining GINS1 BOSS Text Mining GJA1 BOSS Text Mining GPR182 BOSS Text Mining GPX1 BOSS Text Mining HBB BOSS Text Mining HEBP1 BOSS Text Mining HERC2 BOSS Text Mining HMOX1 BOSS Text Mining HSPA5 BOSS Text Mining HTR2C BOSS Text Mining HTR4 BOSS Text Mining ICAM1 BOSS Text Mining ICK BOSS Text Mining IDE BOSS Text Mining IDO1 BOSS Text Mining IFNG BOSS Text Mining IGF1 BOSS Text Mining IGFBP1 BOSS Text Mining IGHD2-15 BOSS Text Mining IL10 BOSS Text Mining IL1A BOSS Text Mining IL1B BOSS Text Mining IL2 BOSS Text Mining IL27 BOSS Text Mining IL2RA BOSS Text Mining IL4 BOSS Text Mining IL6 BOSS Text Mining INS BOSS Text Mining INSR BOSS Text Mining IRF6 BOSS Text Mining IRS4 BOSS Text Mining ISYNA1 BOSS Text Mining JAK2 BOSS Text Mining KISS1 BOSS Text Mining KRIT1 BOSS Text Mining LDHA BOSS Text Mining LEP BOSS Text Mining LNPEP BOSS Text Mining LPO BOSS Text Mining MAOB BOSS Text Mining MAPK3 BOSS Text Mining MAPK8 BOSS Text Mining MMP2 BOSS Text Mining MMP9 BOSS Text Mining MPO BOSS Text Mining MPP2 BOSS Text Mining MRPL23 BOSS Text Mining MTG1 BOSS Text Mining MTNR1B BOSS Text Mining MTOR BOSS Text Mining MTR BOSS Text Mining NES BOSS Text Mining NFKB1 BOSS Text Mining NFKB2 BOSS Text Mining NONO BOSS Text Mining NOS3 BOSS Text Mining NPAS2 BOSS Text Mining NPFF BOSS Text Mining NPFFR1 BOSS Text Mining NPY BOSS Text Mining NQO2 BOSS Text Mining NR3C1 BOSS Text Mining NSG1 BOSS Text Mining OCLN BOSS Text Mining OPRM1 BOSS Text Mining OPTN BOSS Text Mining PAGR1 BOSS Text Mining PARP2 BOSS Text Mining PCNA BOSS Text Mining PER2 BOSS Text Mining PER3 BOSS Text Mining PGAP3 BOSS Text Mining PGR BOSS Text Mining PNPLA3 BOSS Text Mining POLD4 BOSS Text Mining POMC BOSS Text Mining PPARG BOSS Text Mining PPT1 BOSS Text Mining PRDX2 BOSS Text Mining PRG4 BOSS Text Mining PRL BOSS Text Mining PRRT2 BOSS Text Mining PTK2B BOSS Text Mining RAB8A BOSS Text Mining REXO1L1P BOSS Text Mining RHO BOSS Text Mining RHOC BOSS Text Mining RHOD BOSS Text Mining RNASEH2A BOSS Text Mining ROS1 BOSS Text Mining RUNX2 BOSS Text Mining SETD2 BOSS Text Mining SIL1 BOSS Text Mining SIRT1 BOSS Text Mining SLC25A20 BOSS Text Mining SLC26A1 BOSS Text Mining SLC6A3 BOSS Text Mining SLC7A1 BOSS Text Mining SOD1 BOSS Text Mining SPARC BOSS Text Mining SRI BOSS Text Mining SST BOSS Text Mining ST3GAL4 BOSS Text Mining STAT1 BOSS Text Mining STAT3 BOSS Text Mining SYP BOSS Text Mining TAOK1 BOSS Text Mining TAS2R62P BOSS Text Mining TCOF1 BOSS Text Mining TLR4 BOSS Text Mining TNF BOSS Text Mining TP53 BOSS Text Mining TPM3 BOSS Text Mining TRAPPC9 BOSS Text Mining TRH BOSS Text Mining TYRP1 BOSS Text Mining VEGFA BOSS Text Mining VIP PubChem AhR Potency (uM) uM 49.299 AHR - GI(Protien) : PubChem None uM CYP1A2 - GI(Protien) : PubChem None uM CYP1A2 - GI(Protien) : PubChem Potency uM 19.953 CYP3A4 - GI(Protien) : PubChem Potency-Replicate_1 uM 55.315 ESR1 - GI(Protien) : PubChem None uM HTR2B GI(Protien) : PubChem None uM MAP4K2 - GI(Protien) : ChEMBL AC50 nM 5011.870 CYP1A2 - Target : CHEMBL3356 ChEMBL Potency nM 19952.600 CYP3A4 - Target : CHEMBL340
Download gene sets	gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).