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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : Boss - myricetin from myrica cerifera leaf and bark

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Collection	D4 : Boss
Chemical Name	myricetin from myrica cerifera leaf and bark ( From PubChem : MYRICETIN )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Approved Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 318.235 g/mol 6 8 1.6936 False(3/4)
Structure
InChI	InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H
InChIKey	IKMDFBPHZNJCSN-UHFFFAOYSA-N
Links
Gene (76 / 175) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining ATP1B1 BOSS Text Mining AURKB BOSS Text Mining BBS9 BOSS Text Mining CASP3 BOSS Text Mining CDT1 BOSS Text Mining CYCS BOSS Text Mining CYGB BOSS Text Mining CYP2C8 BOSS Text Mining GPX1 BOSS Text Mining INS BOSS Text Mining MMP1 BOSS Text Mining MMP9 BOSS Text Mining SLC7A1 BOSS Text Mining TNF PubChem None uM ABL1 - GI(Protien) : PubChem Potency uM 3.548 ALDH1A1 - GI(Protien) : PubChem Potency uM 8.912 ALDH1A1 - GI(Protien) : PubChem Potency uM 12.589 ALDH1A1 - GI(Protien) : PubChem Potency uM 1.585 ALOX15 - GI(Protien) : PubChem Potency uM 2.512 ALOX15 - GI(Protien) : PubChem IC50_Mean uM 33.200 ALPL - GI(Protien) : PubChem EC50_Mean uM 32.300 ALPPL2 - GI(Protien) : PubChem IC50_Mean uM 17.500 APOBEC3A - GI(Protien) : PubChem IC50_Mean uM 2.390 APOBEC3G - GI(Protien) : PubChem None uM APOBEC3G - GI(Protien) : PubChem None uM APOBEC3G - GI(Protien) : PubChem Potency uM 22.387 BAZ2B - GI(Protien) : PubChem Potency uM 14.125 BLM - GI(Protien) : PubChem Potency uM 14.125 BLM - GI(Protien) : PubChem AC50_uM uM 0.461 CASP6 - GI(Protien) : PubChem None uM CASP6 - GI(Protien) : PubChem Potency uM 14.125 CBX1 - GI(Protien) : PubChem None uM CLK3 - GI(Protien) : PubChem None uM CYP1A2 - GI(Protien) : PubChem None uM CYP1A2 - GI(Protien) : PubChem Potency uM 10.000 CYP2C19 - GI(Protien) : PubChem Potency uM 10.000 CYP2C9 - GI(Protien) : PubChem Potency uM 12.589 CYP2C9 - GI(Protien) : PubChem None uM CYP2C9 - GI(Protien) : PubChem Potency uM 0.562 EHMT2 - GI(Protien) : PubChem Potency uM 1.683 EHMT2 - GI(Protien) : PubChem Potency uM 1.995 EHMT2 - GI(Protien) : PubChem Potency uM 2.818 EHMT2 - GI(Protien) : PubChem None uM ESR1 - GI(Protien) : PubChem None uM EZH2 - GI(Protien) : PubChem Potency uM 1.000 FEN1 - GI(Protien) : PubChem Potency uM 1.413 FEN1 - GI(Protien) : PubChem Potency uM 1.500 FEN1 - GI(Protien) : PubChem Potency uM 1.500 FEN1 - GI(Protien) : PubChem Potency uM 2.239 FEN1 - GI(Protien) : PubChem Potency uM 2.686 FEN1 - GI(Protien) : PubChem AbsAC1_uM uM 4.370 FGF22 - GI(Protien) : PubChem None uM FGF22 - GI(Protien) : PubChem None uM GFER - GI(Protien) : PubChem Potency uM 3.981 GLS - GI(Protien) : PubChem AC50_uM uM 4.133 GSK3A - GI(Protien) : PubChem None uM GSK3A - GI(Protien) : PubChem None uM GSTO1 - GI(Protien) : PubChem None uM GSTO1 - GI(Protien) : PubChem Potency uM 7.943 HPGD - GI(Protien) : PubChem Potency uM 10.000 HPGD - GI(Protien) : PubChem Potency uM 12.589 HPGD - GI(Protien) : PubChem None uM HSP90AA1 - GI(Protien) : PubChem None uM ITGA4 - GI(Protien) : PubChem Potency uM 0.150 L3MBTL1 - GI(Protien) : PubChem Potency uM 0.447 L3MBTL1 - GI(Protien) : PubChem Potency uM 7.080 MAPT - GI(Protien) : PubChem Potency uM 10.000 MAPT - GI(Protien) : PubChem None uM MBD2 - GI(Protien) : PubChem Potency uM 6.310 MPHOSPH8 - GI(Protien) : PubChem Potency uM 8.437 MPHOSPH8 - GI(Protien) : PubChem None uM PAFAH1B2 - GI(Protien) : PubChem None uM PAFAH1B3 - GI(Protien) : PubChem None uM PIM2 - GI(Protien) : PubChem None uM PLA2G7 - GI(Protien) : PubChem None uM PLA2G7 - GI(Protien) : PubChem Potency uM 9.466 PLK1 - GI(Protien) : PubChem Potency uM 0.200 POLB - GI(Protien) : PubChem Potency uM 0.708 POLH - GI(Protien) : PubChem Potency uM 1.259 POLH - GI(Protien) : PubChem Potency uM 1.694 POLH - GI(Protien) : PubChem Potency uM 0.398 POLI - GI(Protien) : PubChem Potency uM 1.062 POLI - GI(Protien) : PubChem Potency uM 1.122 POLI - GI(Protien) : PubChem Potency uM 3.162 POLI - GI(Protien) : PubChem Potency uM 0.150 POLK - GI(Protien) : PubChem Potency uM 0.282 POLK - GI(Protien) : PubChem Potency uM 0.299 POLK - GI(Protien) : PubChem Potency uM 0.844 POLK GI(Protien) : PubChem Potency uM 0.947 POLK - GI(Protien) : PubChem Potency uM 1.122 POLK - GI(Protien) : PubChem Potency uM 1.995 POLK - GI(Protien) : PubChem Potency uM 2.239 POLK - GI(Protien) : PubChem Potency uM 2.818 POLK - GI(Protien) : PubChem None uM PREPL - GI(Protien) : PubChem None uM PREPL - GI(Protien) : PubChem None uM PRMT1 - GI(Protien) : PubChem IC50 uM 0.758 PSIP1 - GI(Protien) : PubChem IC50 uM 1.140 PSIP1 - GI(Protien) : PubChem None uM PSIP1 - GI(Protien) : PubChem None uM PSIP1 - GI(Protien) : PubChem None uM PSIP1 - GI(Protien) : PubChem None uM RIN1 - GI(Protien) : PubChem None uM RNASEH1 - GI(Protien) : PubChem None uM SENP1 - GI(Protien) : PubChem None uM SENP8 - GI(Protien) : PubChem EC50_uM uM 17.970 STK33 - GI(Protien) : PubChem None uM STK33 - GI(Protien) : PubChem None uM STK33 - GI(Protien) : PubChem Potency uM 11.220 TDP1 - GI(Protien) : PubChem Potency uM 18.356 TDP1 - GI(Protien) : PubChem Potency uM 10.000 THPO - GI(Protien) : PubChem None uM TRA - GI(Protien) : PubChem None uM TRA - GI(Protien) : PubChem None uM UHRF1 - GI(Protien) : PubChem Potency uM 1.122 WRN - GI(Protien) : ChEMBL Potency nM 8912.500 ALDH1A1 - Target : CHEMBL3577 ChEMBL Potency nM 3548.100 ALDH1A1 - Target : CHEMBL3577 ChEMBL Potency nM 12589.300 ALDH1A1 - Target : CHEMBL3577 ChEMBL Potency nM 1584.900 ALOX15 - Target : CHEMBL2903 ChEMBL Potency nM 2511.900 ALOX15 - Target : CHEMBL2903 ChEMBL IC50 nM 33200.000 ALPL - Target : CHEMBL5979 ChEMBL EC50 nM 32300.000 ALPPL2 - Target : CHEMBL3402 ChEMBL Potency nM 7079.500 APEX1 - Target : CHEMBL5619 ChEMBL Potency nM 354.800 APEX1 - Target : CHEMBL5619 ChEMBL IC50 nM 17500.000 APOBEC3A - Target : CHEMBL1741179 ChEMBL IC50 nM 2390.000 APOBEC3G - Target : CHEMBL1741217 ChEMBL Potency nM 22387.200 BAZ2B - Target : CHEMBL1741220 ChEMBL Potency nM 14125.400 BLM - Target : CHEMBL1293237 ChEMBL Potency nM 14125.400 BLM - Target : CHEMBL1293237 ChEMBL Potency nM 14125.400 CBX1 - Target : CHEMBL1741193 ChEMBL AC50 nM 5011.870 CYP1A2 - Target : CHEMBL3356 ChEMBL AC50 nM 1995.260 CYP1A2 - Target : CHEMBL3356 ChEMBL Potency nM 10000.000 CYP2C19 - Target : CHEMBL3622 ChEMBL AC50 nM 10000.000 CYP2C9 - Target : CHEMBL3397 ChEMBL AC50 nM 12589.200 CYP2C9 - Target : CHEMBL3397 ChEMBL Potency nM 10000.000 CYP2C9 - Target : CHEMBL3397 ChEMBL Potency nM 12589.300 CYP2C9 - Target : CHEMBL3397 ChEMBL Potency nM 1683.400 EHMT2 - Target : CHEMBL6032 ChEMBL Potency nM 562.300 EHMT2 - Target : CHEMBL6032 ChEMBL Potency nM 1995.300 EHMT2 - Target : CHEMBL6032 ChEMBL Potency nM 2818.400 EHMT2 - Target : CHEMBL6032 ChEMBL Potency nM 1500.300 FEN1 - Target : CHEMBL5027 ChEMBL Activity - GPR35 - Target : CHEMBL1293267 ChEMBL Potency nM 10000.000 HPGD - Target : CHEMBL1293255 ChEMBL Potency nM 7943.300 HPGD - Target : CHEMBL1293255 ChEMBL Potency nM 12589.300 HPGD - Target : CHEMBL1293255 ChEMBL Potency nM 7943.300 HSD17B10 - Target : CHEMBL4159 ChEMBL Potency nM 199.500 HSD17B10 - Target : CHEMBL4159 ChEMBL Potency nM 158.500 HSD17B10 - Target : CHEMBL4159 ChEMBL Potency nM 125.900 HSD17B10 - Target : CHEMBL4159 ChEMBL Potency nM 3548.100 KDM4A - Target : CHEMBL5896 ChEMBL Potency nM 2511.900 KDM4E - Target : CHEMBL1293226 ChEMBL Potency nM 7079.500 KDM4E - Target : CHEMBL1293226 ChEMBL Potency nM 4466.800 KDM4E - Target : CHEMBL1293226 ChEMBL Potency nM 446.700 L3MBTL1 - Target : CHEMBL1287622 ChEMBL Potency nM 7079.500 MAPT - Target : CHEMBL1293224 ChEMBL Potency nM 7079.500 MAPT - Target : CHEMBL1293224 ChEMBL Potency nM 10000.000 MAPT - Target : CHEMBL1293224 ChEMBL Potency nM 10000.000 MAPT - Target : CHEMBL1293224 ChEMBL Potency nM 6309.600 MPHOSPH8 - Target : CHEMBL1741210 ChEMBL Potency nM 8436.800 MPHOSPH8 - Target : CHEMBL1741210 ChEMBL Inhibition - PIK3CA - Target : CHEMBL4005 ChEMBL Inhibition - PIK3CA - Target : CHEMBL4005 ChEMBL Potency nM 199.500 POLB - Target : CHEMBL2392 ChEMBL Potency nM 891.300 RECQL - Target : CHEMBL1293236 ChEMBL Potency nM 1412.500 RECQL - Target : CHEMBL1293236 ChEMBL Potency nM 891.300 RECQL - Target : CHEMBL1293236 ChEMBL Potency nM 4466.800 RECQL - Target : CHEMBL1293236 ChEMBL Potency nM 3162.300 RECQL - Target : CHEMBL1293236 ChEMBL Potency nM 10000.000 THPO - Target : CHEMBL1293256 ChEMBL Activity - TOP1 - Target : CHEMBL1781 ChEMBL Activity - TOP2A - Target : CHEMBL1806 ChEMBL Activity - TOP2A - Target : CHEMBL1806 ChEMBL Activity - TOP2A - Target : CHEMBL1806
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