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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : Boss - methylprednisolonum

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Collection	D4 : Boss
Chemical Name	methylprednisolonum ( From PubChem : METHYLPREDNISOLONE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Approved Approved Not Approved Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 374.471 g/mol 3 5 1.8036 True
Structure
InChI	InChI=1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1
InChIKey	VHRSUDSXCMQTMA-PJHHCJLFSA-N
Links
Gene (75 / 86) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining ABO BOSS Text Mining ACE BOSS Text Mining ADAMTS13 BOSS Text Mining ALB BOSS Text Mining AQP4 BOSS Text Mining BCL2 BOSS Text Mining BEST1 BOSS Text Mining C7orf49 BOSS Text Mining CASP3 BOSS Text Mining CD19 BOSS Text Mining CD4 BOSS Text Mining CD8A BOSS Text Mining CDT1 BOSS Text Mining CEACAM1 BOSS Text Mining CSF2 BOSS Text Mining CSF3 BOSS Text Mining CXCL10 BOSS Text Mining CYGB BOSS Text Mining DNTT BOSS Text Mining EFEMP2 BOSS Text Mining EREG BOSS Text Mining F3 BOSS Text Mining F8 BOSS Text Mining F9 BOSS Text Mining FAM109A BOSS Text Mining GAD2 BOSS Text Mining GFAP BOSS Text Mining GPR182 BOSS Text Mining GPX1 BOSS Text Mining HBB BOSS Text Mining ICAM1 BOSS Text Mining IFNA1 BOSS Text Mining IFNB1 BOSS Text Mining IFNG BOSS Text Mining IL10 BOSS Text Mining IL13 BOSS Text Mining IL27 BOSS Text Mining IL4 BOSS Text Mining IL6 BOSS Text Mining INS BOSS Text Mining ISYNA1 BOSS Text Mining LDHA BOSS Text Mining MMP9 BOSS Text Mining MPO BOSS Text Mining MTR BOSS Text Mining MTX1 BOSS Text Mining NCAM1 BOSS Text Mining NELFCD BOSS Text Mining NGF BOSS Text Mining NR3C1 BOSS Text Mining NUP214 BOSS Text Mining OPTN BOSS Text Mining PGAP1 BOSS Text Mining PITX1 BOSS Text Mining PLAU BOSS Text Mining PLXNA3 BOSS Text Mining POMC BOSS Text Mining PTH BOSS Text Mining RHO BOSS Text Mining S100A6 BOSS Text Mining SGCD BOSS Text Mining SLC7A1 BOSS Text Mining SMG1 BOSS Text Mining SP5 BOSS Text Mining SYF2 BOSS Text Mining TLR4 BOSS Text Mining TNF BOSS Text Mining TP53 BOSS Text Mining TRAPPC9 BOSS Text Mining USO1 BOSS Text Mining VEGFA PubChem None uM ABCB1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.019 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.032 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.039 AR - GI(Protien) : PubChem Ratio Potency (uM) uM 0.047 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.049 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.051 AR - GI(Protien) : PubChem None uM CFTR - GI(Protien) : PubChem Potency uM 0.026 NFE2L2 - GI(Protien) : PubChem Potency uM 0.033 NFE2L2 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.021 NR3C1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.031 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.038 NR3C1 - GI(Protien) : PubChem None uM NR3C1 - GI(Protien) : ChEMBL Potency nM 25.900 NFE2L2 - Target : CHEMBL1075094
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