Tan Lab | DSigDB

Gene Set: D4 : Boss - mephalan

Collection

D4 : Boss

Chemical Name

mephalan ( From PubChem : SARCOLYSIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
305.2 g/mol	2	4	2.6253	True

Structure

InChI

InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1

InChIKey

Links

Gene (36 / 43)

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Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			ALB
BOSS	Text Mining			BCL2
BOSS	Text Mining			C7orf49
BOSS	Text Mining			CASP3
BOSS	Text Mining			CD34
BOSS	Text Mining			CDT1
BOSS	Text Mining			CHEK1
BOSS	Text Mining			CSF3
BOSS	Text Mining			EFS
BOSS	Text Mining			ELF3
BOSS	Text Mining			FXYD5
BOSS	Text Mining			HBB
BOSS	Text Mining			IL6
BOSS	Text Mining			LDHA
BOSS	Text Mining			MCL1
BOSS	Text Mining			MYOM2
BOSS	Text Mining			PARP2
BOSS	Text Mining			PR@
BOSS	Text Mining			RAB8A
BOSS	Text Mining			RHO
BOSS	Text Mining			SDC1
BOSS	Text Mining			SLC7A5
BOSS	Text Mining			STAT3
BOSS	Text Mining			TAS2R62P
BOSS	Text Mining			TNF
BOSS	Text Mining			TP53
BOSS	Text Mining			TTR
BOSS	Text Mining			USO1
BOSS	Text Mining			VEGFA
BOSS	Text Mining			YWHAG
PubChem	Potency	uM	31.623	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	0.007	CBX1	-	GI(Protien) :
PubChem	Potency	uM	10.621	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	28.184	MAPT	-	GI(Protien) :
PubChem	Potency	uM	0.224	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.282	TDP1	-	GI(Protien) :
PubChem	Potency	uM	5.173	TDP1	-	GI(Protien) :
PubChem	Potency	uM	7.308	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	31622.800	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	6.700	CBX1	-	Target : CHEMBL1741193
ChEMBL	Potency	nM	10621.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	19952.600	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	28183.800	MAPT	-	Target : CHEMBL1293224

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