Tan Lab | DSigDB

Gene Set: D4 : Boss - lotrimin af powder aerosol

Collection

D4 : Boss

Chemical Name

lotrimin af powder aerosol ( From PubChem : MICONAZOLE NITRATE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
479.141 g/mol	1	3	6.6303	False(3/4)

Structure

InChI

InChI=1S/C18H14Cl4N2O.HNO3/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22;2-1(3)4/h1-8,11,18H,9-10H2;(H,2,3,4)

InChIKey

Links

Gene (21 / 27)

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Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			C7orf49
BOSS	Text Mining			CDH2
BOSS	Text Mining			CYGB
BOSS	Text Mining			CYP2B6
BOSS	Text Mining			CYP2C8
BOSS	Text Mining			HLP
BOSS	Text Mining			PRDX2
BOSS	Text Mining			SLC52A2
PubChem	Potency	uM	22.387	BAZ2B	-	GI(Protien) :
PubChem	Potency	uM	0.398	CYP3A4	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	Potency	uM	11.582	GMNN	-	GI(Protien) :
PubChem	AC50_uM	uM	0.195	HSP90AA1	-	GI(Protien) :
PubChem	Potency	uM	12.995	IDH1	-	GI(Protien) :
PubChem	None	uM		KCNK3	-	GI(Protien) :
PubChem	None	uM		KCNK3	-	GI(Protien) :
PubChem	None	uM		KCNQ1	-	GI(Protien) :
PubChem	None	uM		NPY1R	-	GI(Protien) :
PubChem	None	uM		NPY1R	-	GI(Protien) :
PubChem	None	uM		NPY2R	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	Potency	uM	11.582	TDP1	-	GI(Protien) :
PubChem	Potency	uM	18.356	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	22387.200	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	398.100	CYP3A4	-	Target : CHEMBL340

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