Tan Lab | DSigDB

Gene Set: D4 : Boss - lopac-p-7912

Collection

D4 : Boss

Chemical Name

lopac-p-7912 ( From PubChem : PHLORETIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
274.269 g/mol	4	5	2.3245	True

Structure

InChI

InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2

InChIKey

VGEREEWJJVICBM-UHFFFAOYSA-N

Links

Gene (30 / 59)

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Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			ABCA1
BOSS	Text Mining			AQP7
BOSS	Text Mining			CDT1
BOSS	Text Mining			GCG
BOSS	Text Mining			HERC2
BOSS	Text Mining			INS
BOSS	Text Mining			SLC2A2
BOSS	Text Mining			SLC5A1
PubChem	Ratio Potency (uM)	uM	48.203	AR	-	GI(Protien) :
PubChem	Potency	uM	2.686	ARSA	-	GI(Protien) :
PubChem	Potency	uM	28.184	ATM	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	3.981	CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	2.512	CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	1.995	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.965	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	14.117	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	19.178	ESR1	-	GI(Protien) :
PubChem	AbsAC1_uM	uM	1.740	FGF22	-	GI(Protien) :
PubChem	AbsAC0.54_uM	uM	2.950	FGF22	-	GI(Protien) :
PubChem	None	uM		FGF22	-	GI(Protien) :
PubChem	Potency	uM	31.381	GAA	-	GI(Protien) :
PubChem	Potency	uM	17.783	GBA	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	Potency	uM	25.119	HPGD	-	GI(Protien) :
PubChem	Potency	uM	35.481	HPGD	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	31.325	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	39.435	NFE2L2	-	GI(Protien) :
PubChem	None	uM		PAFAH1B2	-	GI(Protien) :
PubChem	Potency	uM	7.080	POLB	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	Potency	uM	18.888	RGS4	-	GI(Protien) :
PubChem	EC50_uM	uM	21.410	STK33	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
ChEMBL	Potency	nM	28183.800	ATM	-	Target : CHEMBL3797
ChEMBL	AC50	nM	6309.570	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	3981.100	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	12589.200	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	2511.900	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	12589.300	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	10000.000	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	10000.000	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	1995.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	31381.400	GAA	-	Target : CHEMBL2608
ChEMBL	Potency	nM	17782.800	GBA	-	Target : CHEMBL2179
ChEMBL	Potency	nM	25118.900	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	35481.300	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	31622.800	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	7079.500	POLB	-	Target : CHEMBL2392
ChEMBL	Potency	nM	12589.300	RECQL	-	Target : CHEMBL1293236

Download gene sets

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