Tan Lab | DSigDB

Gene Set: D4 : Boss - lilly brand of olanzapine

Collection

D4 : Boss

Chemical Name

lilly brand of olanzapine ( From PubChem : OLANZAPINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
312.432 g/mol	1	5	1.1958	True

Structure

InChI

InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3

InChIKey

WXPNDRBBWZMPQG-UHFFFAOYSA-N

Links

Gene (54 / 65)

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Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			ACHE
BOSS	Text Mining			ADRA1A
BOSS	Text Mining			AGRP
BOSS	Text Mining			AHR
BOSS	Text Mining			BDNF-AS
BOSS	Text Mining			BID
BOSS	Text Mining			BORA
BOSS	Text Mining			CCK
BOSS	Text Mining			CDT1
BOSS	Text Mining			CNR1
BOSS	Text Mining			CYGB
BOSS	Text Mining			CYP2C8
BOSS	Text Mining			DDR2
BOSS	Text Mining			DHX8
BOSS	Text Mining			DRD3
BOSS	Text Mining			FGA
BOSS	Text Mining			GCG
BOSS	Text Mining			GYPE
BOSS	Text Mining			HBB
BOSS	Text Mining			HSD11B1
BOSS	Text Mining			HTR2A
BOSS	Text Mining			HTR2C
BOSS	Text Mining			HTR3A
BOSS	Text Mining			HTR4
BOSS	Text Mining			HTT
BOSS	Text Mining			IGLL2P
BOSS	Text Mining			IL6
BOSS	Text Mining			INS
BOSS	Text Mining			LEP
BOSS	Text Mining			NNT
BOSS	Text Mining			PLXNA3
BOSS	Text Mining			PNPLA3
BOSS	Text Mining			POMC
BOSS	Text Mining			PRL
BOSS	Text Mining			SERPINF2
BOSS	Text Mining			TACR2
BOSS	Text Mining			TNF
BOSS	Text Mining			TNFRSF13C
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CHRM1	-	GI(Protien) :
PubChem	None	uM		CHRM4	-	GI(Protien) :
PubChem	None	uM		CHRM5	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	Potency	uM	5.623	GAA	-	GI(Protien) :
PubChem	AC50_uM	uM	0.369	GFER	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
ChEMBL	Potency	nM	5623.400	GAA	-	Target : CHEMBL2608
ChEMBL	AC50	nM	369.000	GFER	-	Target : CHEMBL1741189

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