DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

Home

Search Gene

Collection

Browse

Download

Help

DSigDB Home

Search Gene

Collections

Browse Gene Sets

Download

Help

Gene Set: D4 : Boss - 4-pregnene-11 corticosteron

---

Collection	D4 : Boss
Chemical Name	4-pregnene-11 corticosteron ( From PubChem : CORTICOSTERONE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 346.461 g/mol 2 4 2.6667 True
Structure
InChI	InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChIKey	OMFXVFTZEKFJBZ-HJTSIMOOSA-N
Links
Gene (180 / 205) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining AATF BOSS Text Mining ABCA1 BOSS Text Mining ACHE BOSS Text Mining AGRP BOSS Text Mining AGT BOSS Text Mining AKR1B1 BOSS Text Mining ALB BOSS Text Mining APLNR BOSS Text Mining APOE BOSS Text Mining APP BOSS Text Mining ARNTL BOSS Text Mining ARTN BOSS Text Mining ATP8A2 BOSS Text Mining AURKB BOSS Text Mining AVPR1A BOSS Text Mining AVPR1B BOSS Text Mining BBS9 BOSS Text Mining BCL2 BOSS Text Mining BDNF-AS BOSS Text Mining BORA BOSS Text Mining C7orf49 BOSS Text Mining CA3 BOSS Text Mining CACNA1S BOSS Text Mining CASP3 BOSS Text Mining CBL BOSS Text Mining CCK BOSS Text Mining CD4 BOSS Text Mining CD8A BOSS Text Mining CDCA7L BOSS Text Mining CDT1 BOSS Text Mining CEACAM1 BOSS Text Mining CFB BOSS Text Mining CNR1 BOSS Text Mining COMT BOSS Text Mining CORT BOSS Text Mining COX8C BOSS Text Mining CPB1 BOSS Text Mining CRH BOSS Text Mining CRHR2 BOSS Text Mining CRY1 BOSS Text Mining CRY2 BOSS Text Mining CSF2 BOSS Text Mining CYCS BOSS Text Mining CYGB BOSS Text Mining CYP11A1 BOSS Text Mining CYP17A1 BOSS Text Mining CYP21A2 BOSS Text Mining CYP2B6 BOSS Text Mining CYP2C8 BOSS Text Mining DCX BOSS Text Mining DDR2 BOSS Text Mining DECR1 BOSS Text Mining DLX3 BOSS Text Mining EPHB2 BOSS Text Mining EREG BOSS Text Mining ESR1 BOSS Text Mining ESR2 BOSS Text Mining FAM109A BOSS Text Mining FDX1 BOSS Text Mining FST BOSS Text Mining G6PC BOSS Text Mining GAD2 BOSS Text Mining GCG BOSS Text Mining GCH1 BOSS Text Mining GFAP BOSS Text Mining GGH BOSS Text Mining GHSR BOSS Text Mining GINS1 BOSS Text Mining GLP1R BOSS Text Mining GPR182 BOSS Text Mining GPX1 BOSS Text Mining GRIA1 BOSS Text Mining GRIN2A BOSS Text Mining GRIN2B BOSS Text Mining GRM2 BOSS Text Mining GRM5 BOSS Text Mining HBB BOSS Text Mining HESX1 BOSS Text Mining HSD11B1 BOSS Text Mining HSD11B2 BOSS Text Mining HSPA2 BOSS Text Mining HSPA4 BOSS Text Mining HSPB2 BOSS Text Mining HTR4 BOSS Text Mining HTT BOSS Text Mining ICAM1 BOSS Text Mining IDE BOSS Text Mining IFNG BOSS Text Mining IGF1 BOSS Text Mining IGFBP1 BOSS Text Mining IL10 BOSS Text Mining IL12B BOSS Text Mining IL13 BOSS Text Mining IL1B BOSS Text Mining IL2 BOSS Text Mining IL4 BOSS Text Mining IL5 BOSS Text Mining IL6 BOSS Text Mining INS BOSS Text Mining INSR BOSS Text Mining IRF6 BOSS Text Mining IRS4 BOSS Text Mining ISYNA1 BOSS Text Mining KISS1 BOSS Text Mining LDHA BOSS Text Mining LEP BOSS Text Mining LEPR BOSS Text Mining LIPE BOSS Text Mining LOH19CR1 BOSS Text Mining MADD BOSS Text Mining MAOB BOSS Text Mining MAPK3 BOSS Text Mining MC2R BOSS Text Mining MC4R BOSS Text Mining MPO BOSS Text Mining MPP6 BOSS Text Mining MTG1 BOSS Text Mining MTR BOSS Text Mining MZB1 BOSS Text Mining NDOR1 BOSS Text Mining NELFCD BOSS Text Mining NFKB2 BOSS Text Mining NGF BOSS Text Mining NONO BOSS Text Mining NPY BOSS Text Mining NR3C1 BOSS Text Mining NR3C2 BOSS Text Mining NR4A1 BOSS Text Mining NR5A1 BOSS Text Mining NRG1 BOSS Text Mining NSG1 BOSS Text Mining OXTR BOSS Text Mining P2RY2 BOSS Text Mining PAF1 BOSS Text Mining PCK1 BOSS Text Mining PCNA BOSS Text Mining PER2 BOSS Text Mining PGAP3 BOSS Text Mining PGR BOSS Text Mining PLA2G7 BOSS Text Mining PNPLA3 BOSS Text Mining POLD4 BOSS Text Mining POMC BOSS Text Mining PPARG BOSS Text Mining PPT1 BOSS Text Mining PRG4 BOSS Text Mining PRL BOSS Text Mining PTGS1 BOSS Text Mining PTK2B BOSS Text Mining REXO1L1P BOSS Text Mining RHO BOSS Text Mining RNASEH2A BOSS Text Mining SERPINA6 BOSS Text Mining SLC22A2 BOSS Text Mining SLC22A3 BOSS Text Mining SLC25A20 BOSS Text Mining SLC6A3 BOSS Text Mining SLC7A1 BOSS Text Mining SOD1 BOSS Text Mining SST BOSS Text Mining SSTR2 BOSS Text Mining STAR BOSS Text Mining STX2 BOSS Text Mining SYP BOSS Text Mining TACR2 BOSS Text Mining TAT BOSS Text Mining THOC1 BOSS Text Mining TLR2 BOSS Text Mining TLR4 BOSS Text Mining TNF BOSS Text Mining TRAPPC9 BOSS Text Mining TRH BOSS Text Mining TSHR BOSS Text Mining TSPAN1 BOSS Text Mining TYRP1 BOSS Text Mining ZNF234 BOSS Text Mining ZRSR2 PubChem Potency-Replicate_1 uM 0.109 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.122 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.155 AR - GI(Protien) : PubChem Potency uM 0.224 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.275 AR - GI(Protien) : PubChem Ratio Potency (uM) uM 0.292 AR - GI(Protien) : PubChem Ratio Potency (uM) uM 0.312 AR - GI(Protien) : PubChem Potency uM 0.316 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.376 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.601 AR - GI(Protien) : PubChem Ratio Potency (uM) uM 0.882 AR - GI(Protien) : PubChem IC50 uM EIF4H - GI(Protien) : PubChem Potency uM 0.411 NFE2L2 - GI(Protien) : PubChem Potency uM 1.300 NFE2L2 - GI(Protien) : PubChem Potency uM 6.513 NFE2L2 - GI(Protien) : PubChem Ratio Potency (uM) uM 68.729 NFE2L2 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.069 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.084 NR3C1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.123 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.138 NR3C1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.169 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.262 NR3C1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.390 NR3C1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.674 NR3C1 - GI(Protien) : PubChem None uM NR3C1 - GI(Protien) : PubChem None uM NR3C1 - GI(Protien) : ChEMBL Potency nM 6513.100 NFE2L2 - Target : CHEMBL1075094 ChEMBL Potency nM 410.900 NFE2L2 - Target : CHEMBL1075094
Download gene sets	gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).