Tan Lab | DSigDB

Gene Set: D4 : Boss - jspy-st000005

Collection

D4 : Boss

Chemical Name

jspy-st000005 ( From PubChem : NOCODAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
301.32 g/mol	2	6	3.1067	True

Structure

InChI

InChI=1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)

InChIKey

KYRVNWMVYQXFEU-UHFFFAOYSA-N

Links

Gene (48 / 73)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			ACOX2
BOSS	Text Mining			ATP1B1
BOSS	Text Mining			ATP8A2
BOSS	Text Mining			AURKB
BOSS	Text Mining			AURKC
BOSS	Text Mining			BCL2
BOSS	Text Mining			BUB1
BOSS	Text Mining			BUB1B
BOSS	Text Mining			CCNB1
BOSS	Text Mining			CDK1
BOSS	Text Mining			CHEK1
BOSS	Text Mining			CHEK2
BOSS	Text Mining			ELF3
BOSS	Text Mining			F3
BOSS	Text Mining			HPD
BOSS	Text Mining			IDUA
BOSS	Text Mining			IMMT
BOSS	Text Mining			INCENP
BOSS	Text Mining			KIF11
BOSS	Text Mining			MAPK3
BOSS	Text Mining			MXI1
BOSS	Text Mining			NDC80
BOSS	Text Mining			PCNA
BOSS	Text Mining			POTEF
BOSS	Text Mining			RAB5A
BOSS	Text Mining			ROCK1
BOSS	Text Mining			SLC25A20
BOSS	Text Mining			TP53
BOSS	Text Mining			TUBE1
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	3.758	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	5.308	AHR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.190	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.213	AR	-	GI(Protien) :
PubChem	Potency	uM	2.230	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	2.310	ATAD5	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	0.116	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.159	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.211	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.237	GMNN	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.750	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.412	NFE2L2	-	GI(Protien) :
PubChem	IC50	uM	0.833	NR0B1	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	None	uM		PAX8	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	0.046	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.052	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.053	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.075	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.106	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.130	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.141	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.178	TDP1	-	GI(Protien) :
PubChem	None	uM		VDR	-	GI(Protien) :
ChEMBL	Potency	nM	2310.000	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	794.300	CREBBP	-	Target : CHEMBL5747
ChEMBL	AC50	nM	1584.890	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	794.330	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	115.800	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	158.500	GMNN	-	Target : CHEMBL1293278
ChEMBL	Activity	-		HSPB1	-	Target : CHEMBL5976
ChEMBL	Activity	-		HSPB1	-	Target : CHEMBL5976

Download gene sets

gmt, text, Detailed text