Tan Lab | DSigDB

Gene Set: D4 : Boss - iv persantine

Collection

D4 : Boss

Chemical Name

iv persantine ( From PubChem : DIPYRIDAMOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
504.626 g/mol	4	12	0.1124	False(2/4)

Structure

InChI

InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2

InChIKey

IZEKFCXSFNUWAM-UHFFFAOYSA-N

Links

Gene (62 / 112)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			ACE
BOSS	Text Mining			ADA
BOSS	Text Mining			ADORA2B
BOSS	Text Mining			APRT
BOSS	Text Mining			ARSA
BOSS	Text Mining			ATP8A2
BOSS	Text Mining			C7orf49
BOSS	Text Mining			CAD
BOSS	Text Mining			CDT1
BOSS	Text Mining			DDR2
BOSS	Text Mining			EDN1
BOSS	Text Mining			F3
BOSS	Text Mining			F9
BOSS	Text Mining			HBB
BOSS	Text Mining			IGLL1
BOSS	Text Mining			IL6
BOSS	Text Mining			INS
BOSS	Text Mining			PDE5A
BOSS	Text Mining			PLAU
BOSS	Text Mining			REG3A
BOSS	Text Mining			SLC29A1
BOSS	Text Mining			SLC29A2
BOSS	Text Mining			VEGFA
BOSS	Text Mining			WDTC1
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	Potency	uM	0.231	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	0.461	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	31.623	ATM	-	GI(Protien) :
PubChem	None	uM		CRHBP	-	GI(Protien) :
PubChem	None	uM		CRHR2	-	GI(Protien) :
PubChem	Potency	uM	1.259	CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	3.981	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	2.909	DRD1	-	GI(Protien) :
PubChem	Potency	uM	10.000	DRD1	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	Potency	uM	1.778	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	4.467	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	7.080	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	22.387	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	6.993	GMNN	-	GI(Protien) :
PubChem	Potency	uM	11.582	GMNN	-	GI(Protien) :
PubChem	Potency	uM	12.589	GMNN	-	GI(Protien) :
PubChem	Potency	uM	10.000	GNAI1	-	GI(Protien) :
PubChem	IC50	uM	21.068	HSP90AA1	-	GI(Protien) :
PubChem	None	uM		HSP90AA1	-	GI(Protien) :
PubChem	Potency	uM	25.119	KAT2A	-	GI(Protien) :
PubChem	AC50_uM	uM	4.030	KEAP1	-	GI(Protien) :
PubChem	None	uM		KEAP1	-	GI(Protien) :
PubChem	None	uM		MCOLN1	-	GI(Protien) :
PubChem	AC50_uM	uM	4.030	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NFE2L2	-	GI(Protien) :
PubChem	None	uM		NOD2	-	GI(Protien) :
PubChem	None	uM		NOD2	-	GI(Protien) :
PubChem	Potency	uM	11.917	PLK1	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	Potency	uM	10.000	RGS12	-	GI(Protien) :
PubChem	None	uM		RIPK2	-	GI(Protien) :
PubChem	None	uM		RIPK2	-	GI(Protien) :
PubChem	Potency	uM	2.561	TDP1	-	GI(Protien) :
PubChem	Potency	uM	4.555	TDP1	-	GI(Protien) :
PubChem	Potency	uM	14.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
PubChem	Potency	uM	26.609	TDP1	-	GI(Protien) :
PubChem	Potency	uM	39.811	THRB	-	GI(Protien) :
PubChem	None	uM		TLR9	-	GI(Protien) :
PubChem	None	uM		TNNC1	-	GI(Protien) :
PubChem	None	uM		TNNI3	-	GI(Protien) :
PubChem	None	uM		TNNT2	-	GI(Protien) :
PubChem	None	uM		TRHR	-	GI(Protien) :
PubChem	Potency	uM	18.337	TSG101	-	GI(Protien) :
PubChem	Potency	uM	31.623	TSHR	-	GI(Protien) :
PubChem	Potency	uM	22.387	USP1	-	GI(Protien) :
PubChem	Potency	uM	28.184	USP1	-	GI(Protien) :
PubChem	Potency	uM	31.623	USP1	-	GI(Protien) :
ChEMBL	Potency	nM	19952.600	ALOX15B	-	Target : CHEMBL2457
ChEMBL	Potency	nM	231.000	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	461.100	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	31622.800	ATM	-	Target : CHEMBL3797
ChEMBL	Potency	nM	39810.700	BRCA1	-	Target : CHEMBL5990
ChEMBL	Potency	nM	3981.100	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	1258.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	1258.930	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	7943.300	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	10000.000	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	10000.000	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	12589.300	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	10000.000	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	10000.000	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	10000.000	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	2909.100	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	7079.500	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	1778.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	22387.200	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	4466.800	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	12589.300	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	12589.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	IC50	nM	21068.200	HSP90AA1	-	Target : CHEMBL2095165
ChEMBL	IC50	nM	21068.200	HSP90AB1	-	Target : CHEMBL2095165
ChEMBL	Potency	nM	25118.900	KAT2A	-	Target : CHEMBL5501
ChEMBL	Potency	nM	39810.700	THRB	-	Target : CHEMBL1947
ChEMBL	Potency	nM	31622.800	TSHR	-	Target : CHEMBL1963

Download gene sets

gmt, text, Detailed text