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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : Boss - irinotecan hcl trihydrate

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Collection	D4 : Boss
Chemical Name	irinotecan hcl trihydrate ( From PubChem : 136572-09-3 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 677.185 g/mol 5 13 4.576 False(2/4)
Structure
InChI	InChI=1S/C33H38N4O6.ClH.3H2O/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;;;;/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;1H;3*1H2/t33-;;;;/m0..../s1
InChIKey	KLEAIHJJLUAXIQ-JDRGBKBRSA-N
Links
Gene (70 / 71) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining ABCC2 BOSS Text Mining ABCG2 BOSS Text Mining AK5 BOSS Text Mining ALB BOSS Text Mining AURKB BOSS Text Mining BCL2 BOSS Text Mining BRCA1 BOSS Text Mining C7orf49 BOSS Text Mining CASP3 BOSS Text Mining CDKN2A BOSS Text Mining CDT1 BOSS Text Mining CEACAM3 BOSS Text Mining CHEK1 BOSS Text Mining COG3 BOSS Text Mining CROT BOSS Text Mining CSF3 BOSS Text Mining CYGB BOSS Text Mining CYP2C8 BOSS Text Mining DDR2 BOSS Text Mining DHDDS BOSS Text Mining DPYS BOSS Text Mining EGF BOSS Text Mining EGFR BOSS Text Mining ELF3 BOSS Text Mining ENO1 BOSS Text Mining ERBB2 BOSS Text Mining ERBB2 BOSS Text Mining ERCC1 BOSS Text Mining FAM109A BOSS Text Mining FLT1 BOSS Text Mining GYPE BOSS Text Mining H2AFX BOSS Text Mining HBB BOSS Text Mining HLP BOSS Text Mining HRAS BOSS Text Mining IFNA1 BOSS Text Mining IGLL3P BOSS Text Mining IKZF3 BOSS Text Mining IL2 BOSS Text Mining INS BOSS Text Mining KDR BOSS Text Mining KRT6B BOSS Text Mining LDHA BOSS Text Mining MAPK3 BOSS Text Mining MGMT BOSS Text Mining MSH2 BOSS Text Mining MTHFR BOSS Text Mining NFKBIL1 BOSS Text Mining NRAS BOSS Text Mining OPTN BOSS Text Mining PARP2 BOSS Text Mining PGF BOSS Text Mining PIK3CD BOSS Text Mining PLXNA3 BOSS Text Mining POLD4 BOSS Text Mining PPARG BOSS Text Mining PR@ BOSS Text Mining PTEN BOSS Text Mining RPN2 BOSS Text Mining SCARNA5 BOSS Text Mining SLC52A2 BOSS Text Mining TDP1 BOSS Text Mining TENM1 BOSS Text Mining TOP1 BOSS Text Mining TP53 BOSS Text Mining TRAPPC9 BOSS Text Mining TSC1 BOSS Text Mining TYMS BOSS Text Mining UGT1A10 BOSS Text Mining VEGFA BOSS Text Mining XRCC1
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