Tan Lab | DSigDB

Gene Set: D1 - Approved - NALMEFENE

Collection

D1 : Approved

Chemical Name

NALMEFENE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
339.428 g/mol	2	4	2.4504	True

Structure

InChI

InChI=1S/C21H25NO3/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13/h4-5,13,16,19,23-24H,1-3,6-11H2/t16-,19+,20+,21-/m1/s1

InChIKey

WJBLNOPPDWQMCH-MBPVOVBZSA-N

Links

Gene (4 / 14)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Potency	uM	29.849	ESR1	-	GI(Protien) :
PubChem	Kd	uM	0.001	OPRD1		GI(Protien) :
PubChem	Ki	uM	0.009	OPRD1		GI(Protien) :
PubChem	Ki	uM	0.013	OPRD1		GI(Protien) :
PubChem	Ki	uM	0.000	OPRK1		GI(Protien) :
PubChem	Ki	uM	0.001	OPRK1		GI(Protien) :
PubChem	IC50	uM	0.500	OPRK1	-	GI(Protien) :
PubChem	IC50	uM	0.779	OPRK1	-	GI(Protien) :
PubChem		uM		OPRK1		GI(Protien) :
PubChem	Kd	uM	0.000	OPRM1		GI(Protien) :
PubChem	Ki	uM	0.000	OPRM1		GI(Protien) :
PubChem	Ki	uM	0.001	OPRM1		GI(Protien) :
ChEMBL	IC50	nM	779.000	OPRK1	-	Target : CHEMBL237
ChEMBL	IC50	nM	500.000	OPRK1	-	Target : CHEMBL237

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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