Tan Lab | DSigDB

Gene Set: D1 - Approved - DICYCLOMINE

Collection

D1 : Approved

Chemical Name

DICYCLOMINE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
309.487 g/mol	0	3	4.4022	True

Structure

InChI

InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3

InChIKey

Links

Gene (19 / 35)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	0.003	CHRM1	-	GI(Protien) :
PubChem	IC50	uM	0.046	CHRM2	-	GI(Protien) :
PubChem	IC50	uM	0.004	CHRM3	-	GI(Protien) :
PubChem	IC50	uM	0.003	CHRM4	-	GI(Protien) :
PubChem	IC50	uM	0.002	CHRM5	-	GI(Protien) :
PubChem	Potency	uM	29.849	CYP19A1	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP2D6	-	GI(Protien) :
PubChem		uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	2.512	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP3A4	-	GI(Protien) :
PubChem		uM		CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	14.125	DRD1	-	GI(Protien) :
PubChem	IC50	uM	1.210	DRD3	-	GI(Protien) :
PubChem	IC50	uM	1.625	HRH2	-	GI(Protien) :
PubChem	IC50	uM	0.240	HTR2A	-	GI(Protien) :
PubChem	IC50	uM	1.301	HTR2B	-	GI(Protien) :
PubChem	IC50	uM	0.468	HTR2C	-	GI(Protien) :
PubChem	IC50	uM	3.065	HTR6	-	GI(Protien) :
PubChem	IC50	uM	20.591	KCNH2	-	GI(Protien) :
PubChem	IC50	uM	0.005	SIGMAR1	-	GI(Protien) :
ChEMBL	AC50	nM	3981.070	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	12589.200	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	5011.900	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	7943.300	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	7943.280	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	5011.870	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	2511.890	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	5011.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	5011.870	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	2511.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	14125.400	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	33587.500	EHMT2	-	Target : CHEMBL6032

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