Tan Lab | DSigDB

Gene Set: D1 - Approved - VITAMIN D3

Collection

D1 : Approved

Chemical Name

VITAMIN D3

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
384.638 g/mol	1	1	7.619	False(3/4)

Structure

InChI

InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1

InChIKey

QYSXJUFSXHHAJI-YRZJJWOYSA-N

Links

Gene (13 / 26)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem	Potency	uM	15.849	ALOX15	-	GI(Protien) :
PubChem	Potency	uM	19.317	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	67.962	AR	-	GI(Protien) :
PubChem	Potency	uM	31.623	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	15.849	ESR1	-	GI(Protien) :
PubChem	Potency	uM	23.715	GMNN	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	51.398	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	22.387	MAPT	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	20.682	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	21.492	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	23.710	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	54.444	PPARG	-	GI(Protien) :
PubChem	Potency	uM	37.578	RORC	-	GI(Protien) :
PubChem	Potency	uM	25.119	VDR	-	GI(Protien) :
PubChem		uM		VDR		GI(Protien) :
PubChem		uM		VDR		GI(Protien) :
ChEMBL	Potency	nM	15848.900	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	31622.800	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	15848.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	15848.900	ESR1	-	Target : CHEMBL206
ChEMBL	Potency	nM	23715.000	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	22387.200	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	23710.100	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	37578.000	RORC	-	Target : CHEMBL1741186
ChEMBL	Potency	nM	25118.900	VDR	-	Target : CHEMBL1977

Download gene sets

gmt, text, Detailed text