Tan Lab | DSigDB

Gene Set: D1 - Approved - DIAZOXIDE

Collection

D1 : Approved

Chemical Name

DIAZOXIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
230.671 g/mol	1	4	2.527	True

Structure

InChI

InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)

InChIKey

Links

Gene (7 / 22)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem	EC50	uM	8.800	ABCC8		GI(Protien) :
PubChem	EC50	uM	23.500	ABCC8		GI(Protien) :
PubChem	EC50	uM	31.000	ABCC8		GI(Protien) :
PubChem	EC50	uM	33.000	ABCC8		GI(Protien) :
PubChem	EC50	uM	33.000	ABCC8		GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP2D6	-	GI(Protien) :
PubChem		uM		CYP2D6	-	GI(Protien) :
PubChem	EC50	uM	8.800	KCNJ11		GI(Protien) :
PubChem	EC50	uM	23.500	KCNJ11		GI(Protien) :
PubChem	EC50	uM	31.000	KCNJ11		GI(Protien) :
PubChem	EC50	uM	33.000	KCNJ11		GI(Protien) :
PubChem	EC50	uM	33.000	KCNJ11		GI(Protien) :
PubChem		uM		KCNJ11	-	GI(Protien) :
PubChem		uM		KCNJ8	-	GI(Protien) :
ChEMBL	AC50	nM	3162.280	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1995.260	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	7943.300	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	7943.280	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	2818.400	EHMT2	-	Target : CHEMBL6032

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