Tan Lab | DSigDB

Gene Set: D1 - Approved - DINOPROSTONE

Collection

D1 : Approved

Chemical Name

DINOPROSTONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
352.465 g/mol	3	5	3.2511	True

Structure

InChI

InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1

InChIKey

XEYBRNLFEZDVAW-ARSRFYASSA-N

Links

Gene (7 / 25)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	0.029	AR	-	GI(Protien) :
PubChem	Ki	uM	0.009	PTGER1		GI(Protien) :
PubChem	Ki	uM	0.009	PTGER1		GI(Protien) :
PubChem		uM		PTGER1	-	GI(Protien) :
PubChem	IC50	uM	0.002	PTGER2		GI(Protien) :
PubChem	IC50	uM	0.003	PTGER2		GI(Protien) :
PubChem	Ki	uM	0.005	PTGER2		GI(Protien) :
PubChem	Ki	uM	0.005	PTGER2		GI(Protien) :
PubChem	Ki	uM	0.005	PTGER2		GI(Protien) :
PubChem	Potency	uM	0.148	PTGER2	-	GI(Protien) :
PubChem		uM		PTGER2	-	GI(Protien) :
PubChem	Ki	uM	0.000	PTGER3		GI(Protien) :
PubChem	Ki	uM	0.000	PTGER3		GI(Protien) :
PubChem		uM		PTGER3	-	GI(Protien) :
PubChem	IC50	uM	0.000	PTGER4		GI(Protien) :
PubChem	Ki	uM	0.001	PTGER4		GI(Protien) :
PubChem	Ki	uM	0.001	PTGER4		GI(Protien) :
PubChem	Ki	uM	0.001	PTGER4		GI(Protien) :
PubChem	IC50	uM	0.001	PTGER4		GI(Protien) :
PubChem	EC50	uM	0.003	PTGER4		GI(Protien) :
PubChem	IC50	uM	0.004	PTGER4		GI(Protien) :
PubChem		uM		PTGER4	-	GI(Protien) :
PubChem	Potency	uM	0.010	TSHR	-	GI(Protien) :
ChEMBL	Potency	nM	10.000	TSHR	-	Target : CHEMBL1963

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