Tan Lab | DSigDB

Gene Set: D1 - Approved - ORLISTAT

Collection

D1 : Approved

Chemical Name

ORLISTAT

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
495.735 g/mol	1	6	7.9087	False(3/4)

Structure

InChI

InChI=1S/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)/t24-,25-,26-,27-/m0/s1

InChIKey

AHLBNYSZXLDEJQ-FWEHEUNISA-N

Links

Gene (12 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Ki	uM	2.500	CNR1		GI(Protien) :
PubChem	IC50	uM	0.010	DAGLA		GI(Protien) :
PubChem	IC50	uM	0.060	DAGLA		GI(Protien) :
PubChem	IC50	uM	1.000	DAGLA		GI(Protien) :
PubChem	IC50	uM	0.060	DAGLB		GI(Protien) :
PubChem		uM		DAGLB	-	GI(Protien) :
PubChem		uM		DAGLB	-	GI(Protien) :
PubChem		uM		FASN	-	GI(Protien) :
PubChem		uM		FASN		GI(Protien) :
PubChem		uM		LIPF	-	GI(Protien) :
PubChem		uM		PAFAH2	-	GI(Protien) :
PubChem		uM		PAFAH2	-	GI(Protien) :
PubChem		uM		PLA2G7	-	GI(Protien) :
PubChem		uM		PNLIP	-	GI(Protien) :
PubChem	Potency	uM	18.356	TDP1	-	GI(Protien) :
PubChem		uM		TNNC1	-	GI(Protien) :
PubChem		uM		TNNI3	-	GI(Protien) :
PubChem		uM		TNNT2	-	GI(Protien) :
ChEMBL	Activity	-		DAGLA	-	Target : CHEMBL5545
ChEMBL	Activity	-		DAGLB	-	Target : CHEMBL5521
ChEMBL	Activity	-		PNLIP	-	Target : CHEMBL1812

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