Tan Lab | DSigDB

Gene Set: D1 - Approved - CAPSAICIN

Collection

D1 : Approved

Chemical Name

CAPSAICIN

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
305.412 g/mol	2	4	4.1805	True

Structure

InChI

InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+

InChIKey

Links

Gene (10 / 29)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Potency	uM	1.995	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	15.849	ALDH1A1	-	GI(Protien) :
PubChem		uM		CYP19A1	-	GI(Protien) :
PubChem	IC50	uM	3.000	CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	2.512	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	42.163	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	47.277	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	47.277	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	39.811	NR1I2	-	GI(Protien) :
PubChem		uM		PLA2G7	-	GI(Protien) :
PubChem	IC50	uM	1.551	PTGS1	-	GI(Protien) :
PubChem	Potency	uM	8.912	TDP1	-	GI(Protien) :
PubChem	Potency	uM	11.220	TDP1	-	GI(Protien) :
PubChem	Potency	uM	29.855	TDP1	-	GI(Protien) :
PubChem	EC50	uM	0.003	TRPV1		GI(Protien) :
PubChem	EC50	uM	0.004	TRPV1		GI(Protien) :
PubChem	Ki	uM	0.006	TRPV1		GI(Protien) :
PubChem	EC50	uM	0.020	TRPV1		GI(Protien) :
PubChem	EC50	uM	0.040	TRPV1		GI(Protien) :
PubChem	EC50	uM	0.040	TRPV1		GI(Protien) :
PubChem	Potency	uM	0.091	TRPV1	-	GI(Protien) :
PubChem		uM		TRPV1	-	GI(Protien) :
PubChem		uM		TRPV1	-	GI(Protien) :
PubChem		uM		TRPV1	-	GI(Protien) :
ChEMBL	Potency	nM	15848.900	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	1995.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	2511.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	42163.200	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	91.200	TRPV1	-	Target : CHEMBL4794

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