Tan Lab | DSigDB

Gene Set: D1 - Approved - RETINOL

Collection

D1 : Approved

Chemical Name

RETINOL

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
286.452 g/mol	1	1	5.5103	False(3/4)

Structure

InChI

InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

InChIKey

FPIPGXGPPPQFEQ-OVSJKPMPSA-N

Links

Gene (19 / 45)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ADRBK1	-	GI(Protien) :
PubChem	Potency	uM	5.967	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	25.119	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	61.877	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	72.303	AR	-	GI(Protien) :
PubChem	Potency	uM	37.578	CXCL8	-	GI(Protien) :
PubChem	Potency	uM	28.784	CYP19A1	-	GI(Protien) :
PubChem		uM		CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	0.944	ESR1	-	GI(Protien) :
PubChem	Potency	uM	3.162	ESR1	-	GI(Protien) :
PubChem	Potency	uM	7.790	ESR1	-	GI(Protien) :
PubChem	Potency	uM	8.485	ESR1	-	GI(Protien) :
PubChem	Potency	uM	14.960	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	18.122	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	20.491	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	23.710	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	49.584	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	60.191	HSPB1	-	GI(Protien) :
PubChem		uM		HTT	-	GI(Protien) :
PubChem	Potency	uM	14.125	KCNH2		GI(Protien) :
PubChem	Potency	uM	14.125	KCNH2		GI(Protien) :
PubChem		uM		MAPT	-	GI(Protien) :
PubChem	Potency	uM	42.163	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	57.432	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	59.679	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	61.877	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	61.877	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	68.590	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	2.818	NR1I2	-	GI(Protien) :
PubChem	Potency	uM	7.080	NR1I2	-	GI(Protien) :
PubChem	Potency	uM	55.634	NR3C1	-	GI(Protien) :
PubChem		uM		NR3C1	-	GI(Protien) :
PubChem		uM		PPARG	-	GI(Protien) :
PubChem	Kd	uM	0.182	RBP4		GI(Protien) :
PubChem		uM		SIRT5	-	GI(Protien) :
PubChem	Potency	uM	20.596	TDP1	-	GI(Protien) :
PubChem		uM		UCHL5	-	GI(Protien) :
ChEMBL	Potency	nM	5967.200	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	25118.900	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	37578.000	CXCL8	-	Target : CHEMBL2157
ChEMBL	Potency	nM	3162.300	ESR1	-	Target : CHEMBL206
ChEMBL	Potency	nM	14125.400	KCNH2	-	Target : CHEMBL240
ChEMBL	Potency	nM	42163.200	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	68589.600	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Activity	-		RARA	-	Target : CHEMBL2055

Download gene sets

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