Tan Lab | DSigDB

Gene Set: D1 - Approved - LINEZOLID

Collection

D1 : Approved

Chemical Name

LINEZOLID

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
337.346 g/mol	1	7	1.6445	True

Structure

InChI

InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1

InChIKey

TYZROVQLWOKYKF-ZDUSSCGKSA-N

Links

Gene (6 / 11)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM		CYP1A2		GI(Protien) :
PubChem	IC50	uM		CYP2C9		GI(Protien) :
PubChem	IC50	uM		CYP2D6		GI(Protien) :
PubChem	IC50	uM		CYP3A4		GI(Protien) :
PubChem	Potency	uM	13.333	ESR1	-	GI(Protien) :
PubChem	Ki	uM	7.900	MAOA		GI(Protien) :
PubChem	Ki	uM	20.000	MAOA		GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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