Tan Lab | DSigDB

Gene Set: D1 - Approved - AMIODARONE HYDROCHLORIDE

Collection

D1 : Approved

Chemical Name

AMIODARONE HYDROCHLORIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
681.773 g/mol	1	4	7.7382	False(2/4)

Structure

InChI

InChI=1S/C25H29I2NO3.ClH/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3;/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3;1H

InChIKey

ITPDYQOUSLNIHG-UHFFFAOYSA-N

Links

Gene (11 / 22)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem		uM		APAF1	-	GI(Protien) :
PubChem	Potency	uM	43.619	AR	-	GI(Protien) :
PubChem	Potency	uM	43.619	CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	9.200	GMNN	-	GI(Protien) :
PubChem	Potency	uM	23.109	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.079	KCNH2		GI(Protien) :
PubChem	Potency	uM	0.079	KCNH2		GI(Protien) :
PubChem		uM		KCNH2	-	GI(Protien) :
PubChem		uM		MAP4K2	-	GI(Protien) :
PubChem		uM		MAP4K2	-	GI(Protien) :
PubChem	AC50_uM	uM	13.660	MLLT3	-	GI(Protien) :
PubChem		uM		MLLT3	-	GI(Protien) :
PubChem		uM		RAD52	-	GI(Protien) :
PubChem		uM		RAD52	-	GI(Protien) :
PubChem	Potency	uM	39.811	SMPD1	-	GI(Protien) :
PubChem		uM		UBE2N	-	GI(Protien) :
PubChem		uM		UBE2N	-	GI(Protien) :
ChEMBL	Potency	nM	9200.000	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	23109.300	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	79.400	KCNH2	-	Target : CHEMBL240
ChEMBL	Potency	nM	39810.700	SMPD1	-	Target : CHEMBL2760

Download gene sets

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