Tan Lab | DSigDB

Gene Set: D1 - Approved - PRIMOLUT DEPOT

Collection

D1 : Approved

Chemical Name

PRIMOLUT DEPOT

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
428.604 g/mol	0	4	5.9696	False(3/4)

Structure

InChI

InChI=1S/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21-,22+,23+,25+,26+,27+/m1/s1

InChIKey

DOMWKUIIPQCAJU-LJHIYBGHSA-N

Links

Gene (10 / 18)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Ratio Potency (uM)	uM	3.011	AR	-	GI(Protien) :
PubChem	Potency	uM	54.095	CYP19A1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	46.812	HSPB1	-	GI(Protien) :
PubChem		uM		KCNK3	-	GI(Protien) :
PubChem		uM		KCNQ1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	12.828	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	20.596	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	10.000	NPSR1	-	GI(Protien) :
PubChem	Potency	uM	0.194	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	0.268	NR3C1	-	GI(Protien) :
PubChem		uM		NR3C1	-	GI(Protien) :
PubChem		uM		NR3C1	-	GI(Protien) :
PubChem		uM		PGR		GI(Protien) :
PubChem		uM		PGR		GI(Protien) :
PubChem	Potency	uM	18.356	TDP1	-	GI(Protien) :
PubChem	Potency	uM	25.929	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	20596.200	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	10000.000	NPSR1	-	Target : CHEMBL5162

Download gene sets

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