Tan Lab | DSigDB

Gene Set: D1 - Approved - NAPROXEN

Collection

D1 : Approved

Chemical Name

NAPROXEN

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
230.259 g/mol	1	3	3.0365	True

Structure

InChI

InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1

InChIKey

CMWTZPSULFXXJA-VIFPVBQESA-N

Links

Gene (9 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	31.300	AKR1C2		GI(Protien) :
PubChem	IC50	uM	0.480	AKR1C3		GI(Protien) :
PubChem	IC50	uM	1.100	AKR1C3		GI(Protien) :
PubChem		uM		CYP1A2		GI(Protien) :
PubChem		uM		CYP2C19		GI(Protien) :
PubChem		uM		CYP2C9		GI(Protien) :
PubChem		uM		CYP2D6		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem	IC50	uM	0.211	PTGS1	-	GI(Protien) :
PubChem		uM		PTGS1		GI(Protien) :
PubChem		uM		PTGS1		GI(Protien) :
PubChem		uM		PTGS1		GI(Protien) :
PubChem		uM		PTGS1		GI(Protien) :
PubChem	IC50	uM	12.400	PTGS2		GI(Protien) :
PubChem	IC50	uM	12.400	PTGS2		GI(Protien) :
PubChem	IC50	uM	17.001	PTGS2	-	GI(Protien) :
PubChem		uM		PTGS2		GI(Protien) :
PubChem		uM		PTGS2		GI(Protien) :
PubChem		uM		PTGS2		GI(Protien) :
PubChem		uM		PTGS2		GI(Protien) :

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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