Tan Lab | DSigDB

Gene Set: D1 - Approved - EZETIMIBE

Collection

D1 : Approved

Chemical Name

EZETIMIBE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
409.425 g/mol	2	4	4.9533	True

Structure

InChI

InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1

InChIKey

OLNTVTPDXPETLC-XPWALMASSA-N

Links

Gene (6 / 7)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		CACNA1H	-	GI(Protien) :
PubChem		uM		NPC1L1	-	GI(Protien) :
PubChem	Potency	uM	5.012	NPSR1	-	GI(Protien) :
PubChem		uM		PPARG	-	GI(Protien) :
PubChem	Km	uM	42.000	UGT1A4		GI(Protien) :
PubChem	Km	uM	21.000	UGT2B7		GI(Protien) :
ChEMBL	Potency	nM	5011.900	NPSR1	-	Target : CHEMBL5162

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).