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Gene Set: D1 - Approved - IRINOTECAN HYDROCHLORIDE

Collection D1 : Approved
Chemical Name IRINOTECAN HYDROCHLORIDE
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
623.139 g/mol 2 10 4.7689 False(3/4)
Structure
InChI InChI=1S/C33H38N4O6.ClH/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;1H/t33-;/m0./s1
InChIKey GURKHSYORGJETM-WAQYZQTGSA-N
Links

Gene (5 / 10)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
PubChem PotencyuM3.378AR-GI(Protien) :
PubChem Ratio Potency (uM)uM3.647AR-GI(Protien) :
PubChem AR Potency (uM)uM8.742AR-GI(Protien) :
PubChem PotencyuM11.883ESR1-GI(Protien) :
PubChem ER Potency (uM)uM19.570ESR1-GI(Protien) :
PubChem PotencyuM2.372TDP1-GI(Protien) :
PubChem PotencyuM2.372TDP1-GI(Protien) :
PubChem PotencyuM2.660TP53-GI(Protien) :
PubChem Ratio Potency (uM)uM5.011TP53-GI(Protien) :
ChEMBLPotencynM25118.900HSD17B10
-Target : CHEMBL4159
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