Tan Lab | DSigDB

Gene Set: D1 - Approved - LOPERAMIDE HYDROCHLORIDE

Collection

D1 : Approved

Chemical Name

LOPERAMIDE HYDROCHLORIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
513.498 g/mol	2	4	5.8279	False(2/4)

Structure

InChI

InChI=1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H

InChIKey

PGYPOBZJRVSMDS-UHFFFAOYSA-N

Links

Gene (18 / 25)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem		uM		BARD1	-	GI(Protien) :
PubChem		uM		BRCA1	-	GI(Protien) :
PubChem		uM		CACNA1H	-	GI(Protien) :
PubChem		uM		CFTR	-	GI(Protien) :
PubChem		uM		DRD1	-	GI(Protien) :
PubChem		uM		DRD3	-	GI(Protien) :
PubChem	Potency	uM	18.356	IDH1	-	GI(Protien) :
PubChem		uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	0.398	KCNH2		GI(Protien) :
PubChem	Potency	uM	0.398	KCNH2		GI(Protien) :
PubChem		uM		MAP1LC3A	-	GI(Protien) :
PubChem		uM		MAP4K2	-	GI(Protien) :
PubChem		uM		MDM2	-	GI(Protien) :
PubChem		uM		MDM4	-	GI(Protien) :
PubChem		uM		NPY2R	-	GI(Protien) :
PubChem		uM		NPY2R	-	GI(Protien) :
PubChem		uM		OPRD1	-	GI(Protien) :
PubChem		uM		OPRM1		GI(Protien) :
PubChem		uM		OPRM1		GI(Protien) :
PubChem		uM		OPRM1	-	GI(Protien) :
PubChem	Potency	uM	5.173	TDP1	-	GI(Protien) :
PubChem	Potency	uM	8.200	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	18356.400	IDH1	-	Target : CHEMBL2007625
ChEMBL	Potency	nM	398.100	KCNH2	-	Target : CHEMBL240

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