Tan Lab | DSigDB

Gene Set: D1 - Approved - PRAZOSIN HYDROCHLORIDE

Collection

D1 : Approved

Chemical Name

PRAZOSIN HYDROCHLORIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
419.862 g/mol	2	9	3.1707	True

Structure

InChI

InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H

InChIKey

WFXFYZULCQKPIP-UHFFFAOYSA-N

Links

Gene (17 / 30)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ADRA1A	-	GI(Protien) :
PubChem		uM		ADRA1B	-	GI(Protien) :
PubChem		uM		ADRA1D	-	GI(Protien) :
PubChem		uM		BARD1	-	GI(Protien) :
PubChem		uM		BRCA1	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	3.663	GMNN	-	GI(Protien) :
PubChem	Potency	uM	4.109	GMNN	-	GI(Protien) :
PubChem	Potency	uM	15.849	GMNN	-	GI(Protien) :
PubChem		uM		IL1B	-	GI(Protien) :
PubChem		uM		MCL1	-	GI(Protien) :
PubChem		uM		MCL1	-	GI(Protien) :
PubChem		uM		MDM2	-	GI(Protien) :
PubChem		uM		MDM2	-	GI(Protien) :
PubChem		uM		MDM4	-	GI(Protien) :
PubChem		uM		MDM4	-	GI(Protien) :
PubChem	Potency	uM	100.000	POLK	-	GI(Protien) :
PubChem	AC50_uM	uM	56.630	RAD54L	-	GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
PubChem	Potency	uM	14.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	15848.900	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	4109.500	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	3662.600	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	14125.400	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	100000.000	POLK	-	Target : CHEMBL5365
ChEMBL	AC50	nM	56630.000	RAD54L	-	Target : CHEMBL2146297

Download gene sets

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