Tan Lab | DSigDB

Gene Set: D1 - Approved - TELMISARTAN

Collection

D1 : Approved

Chemical Name

TELMISARTAN

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
514.617 g/mol	1	6	7.2644	False(2/4)

Structure

InChI

InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)

InChIKey

RMMXLENWKUUMAY-UHFFFAOYSA-N

Links

Gene (11 / 27)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	0.000	AGTR1		GI(Protien) :
PubChem	IC50	uM	0.000	AGTR1		GI(Protien) :
PubChem	IC50	uM	0.001	AGTR1		GI(Protien) :
PubChem	IC50	uM	0.002	AGTR1		GI(Protien) :
PubChem		uM		AGTR1		GI(Protien) :
PubChem		uM		AGTR1		GI(Protien) :
PubChem	Ratio Potency (uM)	uM	23.708	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	26.601	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	1.259	NPSR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.601	PPARG	-	GI(Protien) :
PubChem	EC50	uM	1.520	PPARG		GI(Protien) :
PubChem	EC50	uM	1.520	PPARG		GI(Protien) :
PubChem	EC50	uM	2.020	PPARG		GI(Protien) :
PubChem	EC50	uM	2.020	PPARG		GI(Protien) :
PubChem	EC50	uM	3.400	PPARG		GI(Protien) :
PubChem	IC50	uM	12.200	PPARG		GI(Protien) :
PubChem		uM		PPARG	-	GI(Protien) :
PubChem		uM		SLC12A5	-	GI(Protien) :
PubChem	IC50	uM	17.900	SLC47A1		GI(Protien) :
PubChem		uM		SLC6A3	-	GI(Protien) :
PubChem		uM		SLC6A3	-	GI(Protien) :
PubChem	Potency	uM	50.119	USP1	-	GI(Protien) :
ChEMBL	Potency	nM	4466.800	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	3162.300	GNAS	-	Target : CHEMBL4377
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	1258.900	NPSR1	-	Target : CHEMBL5162
ChEMBL	Potency	nM	50118.700	USP1	-	Target : CHEMBL1795087

Download gene sets

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