Tan Lab | DSigDB

Gene Set: D1 - Approved - CHLORAMBUCIL

Collection

D1 : Approved

Chemical Name

CHLORAMBUCIL

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
304.212 g/mol	1	3	3.3779	True

Structure

InChI

InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)

InChIKey

Links

Gene (9 / 28)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	ATAD5 Potency (uM)	uM	61.379	ATAD5	-	GI(Protien) :
PubChem	ATAD5 Potency (uM)	uM	63.522	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	56.234	BAZ2B	-	GI(Protien) :
PubChem	AC50_uM	uM	0.005	GFER	-	GI(Protien) :
PubChem		uM		GFER	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	66.276	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	8.912	NFKB1	-	GI(Protien) :
PubChem	Potency	uM	66.824	RORC	-	GI(Protien) :
PubChem		uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	0.461	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.562	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.651	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.891	TDP1	-	GI(Protien) :
PubChem	Potency	uM	14.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	22.387	TP53	-	GI(Protien) :
PubChem	Potency	uM	23.710	TP53	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	23.710	TP53	-	GI(Protien) :
PubChem	Potency	uM	34.376	TP53	-	GI(Protien) :
PubChem	Potency	uM	35.481	TP53	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	43.277	TP53	-	GI(Protien) :
PubChem	Potency	uM	61.379	TP53	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	61.379	TP53	-	GI(Protien) :
ChEMBL	Potency	nM	56234.100	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	AC50	nM	5.000	GFER	-	Target : CHEMBL1741189
ChEMBL	Potency	nM	8912.500	NFKB1	-	Target : CHEMBL3251
ChEMBL	Potency	nM	66824.200	RORC	-	Target : CHEMBL1741186
ChEMBL	Potency	nM	35481.300	TP53	-	Target : CHEMBL4096
ChEMBL	Potency	nM	22387.200	TP53	-	Target : CHEMBL4096

Download gene sets