Tan Lab | DSigDB

Gene Set: D1 - Approved - IMIQUIMOD

Collection

D1 : Approved

Chemical Name

IMIQUIMOD

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
240.304 g/mol	1	4	3.4039	True

Structure

InChI

InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)

InChIKey

DOUYETYNHWVLEO-UHFFFAOYSA-N

Links

Gene (6 / 11)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	5.320	ADORA2A	-	GI(Protien) :
PubChem	IC50	uM	2.621	ADRA1D	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	9.439	AHR	-	GI(Protien) :
PubChem	Potency	uM	9.439	AHR	-	GI(Protien) :
PubChem	Potency	uM	0.581	GMNN	-	GI(Protien) :
PubChem	IC50	uM	1.506	HRH2	-	GI(Protien) :
PubChem	EC50	uM	2.120	TLR7		GI(Protien) :
PubChem	EC50	uM	10.700	TLR7		GI(Protien) :
PubChem	EC50	uM	12.100	TLR7		GI(Protien) :
PubChem		uM		TLR7		GI(Protien) :
ChEMBL	Potency	nM	580.500	GMNN	-	Target : CHEMBL1293278

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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