Tan Lab | DSigDB

Gene Set: D1 - Approved - PERGOLIDE MESYLATE

Collection

D1 : Approved

Chemical Name

PERGOLIDE MESYLATE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
410.594 g/mol	2	5	4.7938	True

Structure

InChI

InChI=1S/C19H26N2S.CH4O3S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21;1-5(2,3)4/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3;1H3,(H,2,3,4)/t13-,16?,18?;/m1./s1

InChIKey

UWCVGPLTGZWHGS-QWJYQPCHSA-N

Links

Gene (11 / 24)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem		uM		DRD1	-	GI(Protien) :
PubChem		uM		DRD1	-	GI(Protien) :
PubChem		uM		DRD1	-	GI(Protien) :
PubChem		uM		DRD2	-	GI(Protien) :
PubChem		uM		DRD2	-	GI(Protien) :
PubChem		uM		DRD2	-	GI(Protien) :
PubChem		uM		DRD2	-	GI(Protien) :
PubChem		uM		DRD2	-	GI(Protien) :
PubChem	Potency	uM	0.020	DRD3	-	GI(Protien) :
PubChem		uM		DRD3	-	GI(Protien) :
PubChem		uM		DRD3	-	GI(Protien) :
PubChem		uM		DRD3	-	GI(Protien) :
PubChem		uM		DRD4	-	GI(Protien) :
PubChem		uM		DRD5	-	GI(Protien) :
PubChem	IC50	uM		EIF4H	-	GI(Protien) :
PubChem	Potency	uM	14.125	ERG	-	GI(Protien) :
PubChem		uM		HTR5A	-	GI(Protien) :
PubChem		uM		HTR5A	-	GI(Protien) :
PubChem	Potency	uM	1.995	KCNH2		GI(Protien) :
PubChem	Potency	uM	1.995	KCNH2		GI(Protien) :
PubChem	IC50	uM		PABPC1	-	GI(Protien) :
ChEMBL	Potency	nM	14125.400	ERG	-	Target : CHEMBL1293191
ChEMBL	Potency	nM	1995.300	KCNH2	-	Target : CHEMBL240

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