Tan Lab | DSigDB

Gene Set: D1 - Approved - CAPTOPRIL

Collection

D1 : Approved

Chemical Name

CAPTOPRIL

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
217.285 g/mol	2	5	0.5658	True

Structure

InChI

InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1

InChIKey

FAKRSMQSSFJEIM-RQJHMYQMSA-N

Links

Gene (9 / 17)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	0.000	ACE		GI(Protien) :
PubChem	IC50	uM	0.001	ACE		GI(Protien) :
PubChem	Ki	uM	0.002	ACE		GI(Protien) :
PubChem	IC50	uM	0.021	ACE		GI(Protien) :
PubChem	IC50	uM	0.023	ACE		GI(Protien) :
PubChem		uM		ACE	-	GI(Protien) :
PubChem		uM		DRD2	-	GI(Protien) :
PubChem	IC50	uM	0.070	LTA4H	-	GI(Protien) :
PubChem	IC50	uM	14.000	LTA4H		GI(Protien) :
PubChem		uM		MMP12		GI(Protien) :
PubChem		uM		PSIP1	-	GI(Protien) :
PubChem	Ki	uM	17.000	PTGS1		GI(Protien) :
PubChem	Ki	uM	12.000	PTGS2		GI(Protien) :
PubChem	Ki	uM	0.002	REN		GI(Protien) :
ChEMBL	Potency	nM	7079.500	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	12589.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Inhibition	-		MMP12	-	Target : CHEMBL4393

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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