Tan Lab | DSigDB

Gene Set: D1 - Approved - IDARUBICIN

Collection

D1 : Approved

Chemical Name

IDARUBICIN

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
497.494 g/mol	5	10	1.7206	True

Structure

InChI

InChI=1S/C26H27NO9/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3/t10-,15-,16-,17-,21+,26-/m0/s1

InChIKey

XDXDZDZNSLXDNA-TZNDIEGXSA-N

Links

Gene (24 / 59)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Potency	uM	0.580	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	5.802	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	19.953	ATXN2	-	GI(Protien) :
PubChem	Potency	uM	12.589	BLM	-	GI(Protien) :
PubChem	Potency	uM	12.589	BLM	-	GI(Protien) :
PubChem	Potency	uM	39.811	CBX1	-	GI(Protien) :
PubChem	Potency	uM	2.909	DRD1	-	GI(Protien) :
PubChem	Potency	uM	11.220	DRD1	-	GI(Protien) :
PubChem	Potency	uM	26.680	FEN1	-	GI(Protien) :
PubChem	Potency	uM	26.680	FEN1	-	GI(Protien) :
PubChem		uM		GNAI1	-	GI(Protien) :
PubChem		uM		HSP90AA1	-	GI(Protien) :
PubChem	Potency	uM	0.631	HTT	-	GI(Protien) :
PubChem	Potency	uM	10.000	KCNH2		GI(Protien) :
PubChem	Potency	uM	10.000	KCNH2		GI(Protien) :
PubChem	Potency	uM	3.548	MAPT	-	GI(Protien) :
PubChem	Potency	uM	28.184	MPHOSPH8	-	GI(Protien) :
PubChem	Potency	uM	0.414	MTOR	-	GI(Protien) :
PubChem	Potency	uM	2.328	MTOR	-	GI(Protien) :
PubChem	Potency	uM	14.125	POLB	-	GI(Protien) :
PubChem	Potency	uM	14.125	POLH	-	GI(Protien) :
PubChem	Potency	uM	7.943	POLI	-	GI(Protien) :
PubChem	Potency	uM	7.943	POLK	-	GI(Protien) :
PubChem	Potency	uM	26.680	POLK	-	GI(Protien) :
PubChem		uM		RGS12	-	GI(Protien) :
PubChem	Potency	uM	44.668	THRB	-	GI(Protien) :
PubChem	Potency	uM	39.811	USP1	-	GI(Protien) :
PubChem	Potency	uM	50.119	USP1	-	GI(Protien) :
PubChem		uM		YWHAG	-	GI(Protien) :
ChEMBL	Potency	nM	14125.400	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	15848.900	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	19952.600	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	580.200	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	5802.400	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	19952.600	ATXN2	-	Target : CHEMBL1795085
ChEMBL	Potency	nM	12589.300	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	12589.300	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	39810.700	CBX1	-	Target : CHEMBL1741193
ChEMBL	Potency	nM	2909.100	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	11220.200	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	12589.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	13371.400	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	631.000	HTT	-	Target : CHEMBL5514
ChEMBL	Potency	nM	10000.000	KCNH2	-	Target : CHEMBL240
ChEMBL	Potency	nM	3548.100	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	28183.800	MPHOSPH8	-	Target : CHEMBL1741210
ChEMBL	Potency	nM	2328.100	MTOR	-	Target : CHEMBL2842
ChEMBL	Potency	nM	414.000	MTOR	-	Target : CHEMBL2842
ChEMBL	Potency	nM	14125.400	POLB	-	Target : CHEMBL2392
ChEMBL	Potency	nM	14125.400	POLH	-	Target : CHEMBL5542
ChEMBL	Potency	nM	7943.300	POLI	-	Target : CHEMBL5391
ChEMBL	Potency	nM	26679.500	POLK	-	Target : CHEMBL5365
ChEMBL	Potency	nM	7943.300	POLK	-	Target : CHEMBL5365
ChEMBL	Potency	nM	11220.200	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	35481.300	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	28183.800	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	44668.400	THRB	-	Target : CHEMBL1947
ChEMBL	Potency	nM	50118.700	USP1	-	Target : CHEMBL1795087
ChEMBL	Potency	nM	39810.700	USP1	-	Target : CHEMBL1795087

Download gene sets

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