Tan Lab | DSigDB

Gene Set: D1 - Approved - NITAZOXANIDE

Collection

D1 : Approved

Chemical Name

NITAZOXANIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
307.282 g/mol	1	6	2.8251	True

Structure

InChI

InChI=1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)15(18)19/h2-6H,1H3,(H,13,14,17)

InChIKey

YQNQNVDNTFHQSW-UHFFFAOYSA-N

Links

Gene (25 / 42)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Potency	uM	0.708	AHR	-	GI(Protien) :
PubChem	Potency	uM	10.591	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	12.348	AHR	-	GI(Protien) :
PubChem	Potency	uM	13.961	AR	-	GI(Protien) :
PubChem	ATAD5 Potency (uM)	uM	1.188	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	1.333	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	19.720	CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP3A4	-	GI(Protien) :
PubChem		uM		DRD1	-	GI(Protien) :
PubChem		uM		DRD1	-	GI(Protien) :
PubChem		uM		DRD2	-	GI(Protien) :
PubChem	Potency	uM	0.668	ESR1	-	GI(Protien) :
PubChem		uM		HCRTR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	12.556	HSPB1	-	GI(Protien) :
PubChem		uM		KCNQ1	-	GI(Protien) :
PubChem	Potency	uM	11.220	MAPT	-	GI(Protien) :
PubChem		uM		MCOLN3	-	GI(Protien) :
PubChem	Potency	uM	18.834	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.501	NPC1	-	GI(Protien) :
PubChem	Potency	uM	3.162	NPSR1	-	GI(Protien) :
PubChem		uM		OXTR	-	GI(Protien) :
PubChem		uM		PADI4	-	GI(Protien) :
PubChem	Potency	uM	14.125	PKM	-	GI(Protien) :
PubChem		uM		SLC12A5	-	GI(Protien) :
PubChem		uM		SLC6A3	-	GI(Protien) :
PubChem	Potency	uM	12.589	SMN2	-	GI(Protien) :
PubChem	Potency	uM	5.956	TP53	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	9.715	TP53	-	GI(Protien) :
PubChem	Potency	uM	12.589	TP53	-	GI(Protien) :
PubChem		uM		TSHR		GI(Protien) :
PubChem		uM		TSHR		GI(Protien) :
PubChem	Potency	uM	35.481	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	707.900	AHR	-	Target : CHEMBL3201
ChEMBL	Potency	nM	7943.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	11220.200	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	18833.600	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	501.200	NPC1	-	Target : CHEMBL1293277
ChEMBL	Potency	nM	3162.300	NPSR1	-	Target : CHEMBL5162
ChEMBL	Potency	nM	14125.400	PKM	-	Target : CHEMBL1075189
ChEMBL	Potency	nM	12589.300	SMN2	-	Target : CHEMBL1293232
ChEMBL	Potency	nM	12589.300	TP53	-	Target : CHEMBL4096
ChEMBL	Potency	nM	35481.300	VDR	-	Target : CHEMBL1977

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