Tan Lab | DSigDB

Gene Set: D1 - Approved - (S)-(+)-IBUPROFEN

Collection

D1 : Approved

Chemical Name

(S)-(+)-IBUPROFEN

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
206.281 g/mol	1	2	3.0732	True

Structure

InChI

InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m0/s1

InChIKey

HEFNNWSXXWATRW-JTQLQIEISA-N

Links

Gene (7 / 11)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	42.400	AKR1C2		GI(Protien) :
PubChem	IC50	uM	32.700	AKR1C3		GI(Protien) :
PubChem	IC50	uM	0.100	CXCR1		GI(Protien) :
PubChem	IC50	uM	0.100	CXCR2		GI(Protien) :
PubChem	IC50	uM	0.099	PTGS1		GI(Protien) :
PubChem	IC50	uM	0.105	PTGS1	-	GI(Protien) :
PubChem	IC50	uM	0.730	PTGS2		GI(Protien) :
PubChem		uM		PTGS2		GI(Protien) :
PubChem	Potency	uM	25.119	TARDBP	-	GI(Protien) :
ChEMBL	Inhibition	-		PTGS2	-	Target : CHEMBL230
ChEMBL	Potency	nM	25118.900	TARDBP	-	Target : CHEMBL2362981

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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