Tan Lab | DSigDB

Gene Set: D1 - Approved - HALOFANTRINE

Collection

D1 : Approved

Chemical Name

HALOFANTRINE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
500.424 g/mol	1	2	8.6443	False(2/4)

Structure

InChI

InChI=1S/C26H30Cl2F3NO/c1-3-5-10-32(11-6-4-2)12-9-25(33)23-16-22-21(14-18(27)15-24(22)28)20-13-17(26(29,30)31)7-8-19(20)23/h7-8,13-16,25,33H,3-6,9-12H2,1-2H3/t25-/m0/s1

InChIKey

FOHHNHSLJDZUGQ-VWLOTQADSA-N

Links

Gene (3 / 10)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	0.040	KCNH2		GI(Protien) :
PubChem	IC50	uM	0.195	KCNH2		GI(Protien) :
PubChem	IC50	uM	0.196	KCNH2		GI(Protien) :
PubChem	IC50	uM	0.200	KCNH2		GI(Protien) :
PubChem	IC50	uM	0.200	KCNH2		GI(Protien) :
PubChem	IC50	uM	0.200	KCNH2		GI(Protien) :
PubChem	IC50	uM	0.200	KCNH2		GI(Protien) :
PubChem	Ki	uM	7.500	KCNH2		GI(Protien) :
ChEMBL	AC50	nM	7270.000	HSP90AA1	-	Target : CHEMBL3880
ChEMBL	Potency	nM	14581.000	IDH1	-	Target : CHEMBL2007625

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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