Tan Lab | DSigDB

Gene Set: D1 - Approved - CARBIDOPA

Collection

D1 : Approved

Chemical Name

CARBIDOPA

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
226.229 g/mol	5	6	1.0381	True

Structure

InChI

InChI=1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/m0/s1

InChIKey

Links

Gene (10 / 23)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		CFTR	-	GI(Protien) :
PubChem	Potency	uM	22.387	HPGD	-	GI(Protien) :
PubChem	Potency	uM	28.184	HPGD	-	GI(Protien) :
PubChem	Potency	uM	14.125	MAPT	-	GI(Protien) :
PubChem	Potency	uM	15.849	MAPT	-	GI(Protien) :
PubChem		uM		SENP8	-	GI(Protien) :
PubChem	Potency	uM	4.109	TDP1	-	GI(Protien) :
PubChem	Potency	uM	6.684	TDP1	-	GI(Protien) :
PubChem	Potency	uM	7.308	TDP1	-	GI(Protien) :
PubChem	Potency	uM	9.441	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	7079.500	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	3162.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	10000.000	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	25118.900	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	28183.800	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	22387.200	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	19952.600	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	158.500	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	79432.800	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	2238.700	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	3548.100	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	15848.900	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	14125.400	MAPT	-	Target : CHEMBL1293224

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